Lung cancer screening use and implications of varying eligibility criteria by race and ethnicity: 2019 Behavioral Risk Factor Surveillance System data.

Lung cancer screening use and implications of varying eligibility criteria by race and ethnicity: 2019 Behavioral Risk Factor Surveillance System data.
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DOI:
10.1002/cncr.34098
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发表时间:
2022-05-01
期刊:
影响因子:
6.2
通讯作者:
Taylor, Kathryn L.
Taylor, Kathryn L.
中科院分区:
医学1区
文献类型:
--
作者:
Williams, Randi M.;Li, Tengfei;Luta, George;Wang, Min Qi;Adams-Campbell, Lucile;Meza, Rafael;Tammemagi, Martin C.;Taylor, Kathryn L.

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2021年,美国预防服务工作组(USPSTF)扩大了低剂量计算机断层扫描肺癌筛查(LCS)的资格标准,以减少2013年USPSTF标准导致的种族差异。自2013年USPSTF筛查建议以来,LCS的年发病率缓慢上升。使用2019年行为风险因素监测系统(BRFSS),我们:1)描述2019年LCS的利用率,2)使用2013年与2021年USPSTF标准比较符合LCS资格的百分比,以及3)使用更详细的PLCOm确定符合资格的百分比2012风险预测模型。该分析包括来自参与BRFSS LCS模块的41,544名年龄≥50岁的吸烟史。使用USPSTF 2013标准,2019年有20.7%(95% CI=19.0,22.4)的合格个体接受了LCS。我们比较了2013年和2021年的标准,合格的总体比例从21.0%(95% CI=20.2,21.8)增加到34.7%(95% CI=33.8,35.6)。应用2021年标准,按种族划分的合格比例为:白人35.8%(95% CI=34.8,36.7),黑人28.5%(95% CI=25.2,31.9),西班牙裔18.0%(95% CI=12.4,23.7)。使用与2021年USPSTF标准相当的1.0% 6年阈值,PLCOm2012模型选择了整体和种族更多的个体。使用来自20个州的数据,采用多重插补,我们报告了更高的LCS率相比,以前的BRFSS数据。2021年扩大的标准将导致更多符合筛选条件的个人。然而,基于风险的筛查,利用额外的风险因素可能更具包容性的整体和跨亚组。与之前的数据相比,2019年肺癌筛查率有所提高,2021年扩大的标准将导致更多的合格人群。基于风险的筛查利用了其他风险因素,可能在种族亚组中更具包容性。2013年,肺癌筛查(LCS)被推荐用于高危人群。LCS的年增长率缓慢上升,特别是在黑人中。在某种程度上,这种种族差异导致了2021年标准的扩大。我们使用调查数据:1)描述2019年筛选的人数,2)使用2013年与2021年指南比较符合LCS的百分比,3)使用更详细的标准确定符合条件的百分比。2019年的筛查率有所提高,2021年的标准将使更多的人有资格接受筛查。使用额外的标准可能会识别更多的人有资格进行肺部筛查。
In 2021, the United States Preventive Services Task Force (USPSTF) expanded the eligibility criteria for low-dose computed tomographic lung cancer screening (LCS) to reduce racial disparities that resulted from the 2013 USPSTF criteria. The annual LCS rate has risen slowly since the 2013 USPSTF screening recommendations. Using the 2019 Behavioral Risk Factor Surveillance System (BRFSS), we: 1) describe LCS utilization in 2019, 2) compare the percent eligible for LCS using the 2013 vs. 2021 USPSTF criteria, and 3) determine the percent eligible using the more detailed PLCOm2012 risk-prediction model. The analysis included 41,544 with a smoking history from states participating in the BRFSS LCS module who were ≥50 years old. Using the USPSTF 2013 criteria, 20.7% (95% CI=19.0, 22.4) of eligible individuals underwent LCS in 2019. We compared the 2013 to the 2021 criteria and the overall proportion eligible increased from 21.0% (95% CI=20.2, 21.8) to 34.7% (95% CI=33.8, 35.6). Applying the 2021 criteria, the proportion eligible by race were: 35.8% (95% CI=34.8, 36.7) among Whites, 28.5% (95% CI=25.2, 31.9) among Blacks, and 18.0% (95% CI=12.4, 23.7) among Hispanics. Using the 1.0% 6-year threshold which is comparable to the 2021 USPSTF criteria, the PLCOm2012 model selected more individuals overall and by race. Using data from 20 states and employing multiple imputation, we report higher LCS rates compared to prior BRFSS data. The 2021 expanded criteria will result in a greater number of screen-eligible individuals. However, risk-based screening that utilizes additional risk factors may be more inclusive overall and across subgroups. Compared to prior data, lung cancer screening rates increased in 2019 and the 2021 expanded criteria will result in a greater number of eligible individuals. Risk-based screening that utilizes additional risk factors may be more inclusive across racial subgroups. In 2013, lung cancer screening (LCS) was recommended for high risk individuals. The annual rate of LCS has risen slowly, particularly among Black individuals. In part, this racial disparity resulted in expanded 2021 criteria. We used survey data to: 1) describe the number of people screened in 2019, 2) compare the percent eligible for LCS using the 2013 vs. 2021 guidelines, and 3) determine the percent eligible using more detailed criteria. Screening rates increased in 2019 and the 2021 criteria will result in more individuals eligible for screening. Using additional criteria may identify more individuals eligible for lung screening.
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