Trichomonas vaginalis is associated with pelvic inflammatory disease in women infected with human immunodeficiency virus
Trichomonas vaginalis is associated with pelvic inflammatory disease in women infected with human immunodeficiency virus
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DOI：
10.1086/338399
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发表时间：
2002-02-15
影响因子：
11.8
通讯作者：
Sturm, AW
中科院分区：
文献类型：
--
作者：
Moodley, P;Wilkinson, D;Sturm, AW
We assessed the association between the causative agents of vaginal discharge and pelvic inflammatory disease (PID) among women attending a rural sexually transmitted disease clinic in South Africa; the role played by coinfection with human immunodeficiency virus type 1 (HIV-1) was studied. Vaginal and cervical specimens were obtained to detect Neisseria gonorrhoeae, Chlamydia trachomatis, Trichomonas vaginalis, and bacterial vaginosis. HIV-1 infection was established by use of serum antibody tests. A total of 696 women with vaginal discharge were recruited, 119 of whom had clinical PID. Patients with trichomoniasis had a significantly higher risk of PID than did women without trichomoniasis (P = .03). PID was not associated with any of the other pathogens. When the patients were stratified according to HIV-1 status, the risk of PID in HIV-1-infected patients with T. vaginalis increased significantly (P = .002); no association was found in patients without HIV-1. T. vaginalis infection of the lower genital tract is associated with a clinical diagnosis of PID in HIV-1-infected women.
