Estimation of C. elegans cell- and tissue volumes.
Estimation of C. elegans cell- and tissue volumes.
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DOI：
10.17912/micropub.biology.000345
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发表时间：
2021-01-04
影响因子：
--
通讯作者：
Ewald CY
中科院分区：
文献类型：
--
作者：
Froehlich JJ;Rajewsky N;Ewald CY
虽然秀丽隐杆线虫是研究得最好的模式生物之一，但对其细胞大小和组织的估计仍缺失。在这里，我们使用基于电子显微镜图像的虚拟蠕虫来计算秀丽隐杆线虫的细胞和组织大小的零阶近似。我们得出结论，肠是最大的组织，其次是皮下组织、性腺、体壁肌肉、咽和神经元。因此，我们提供了年轻成年秀丽隐杆线虫的组织体积的近似值。
Although C. elegans is one of the best-studied model organisms, an estimate of its cell sizes and tissues is missing. Here we used the Virtual Worm that is based on electron microscopy images to calculate a zeroth-order approximation of cell and tissue sizes of C. elegans. We conclude that the intestine is the largest tissue, followed by the hypodermis, gonads, body wall muscles, pharynx, and neurons. Thus, we provide an approximation of tissue volumes of young adult C. elegans.