Dimensional complexity of EEG waveforms in neuroleptic-free schizophrenic patients and normal control subjects.
Dimensional complexity of EEG waveforms in neuroleptic-free schizophrenic patients and normal control subjects.
复制标题
未服用抗精神病药物的精神分裂症患者和正常对照受试者脑电图波形的维度复杂性。
DOI：
10.1176/jnp.8.4.436
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发表时间：
1996
期刊：
影响因子：
--
通讯作者：
Nuechterlein,KH
中科院分区：
文献类型：
--
作者：
Hoffmann,RE;Buchsbaum,MS;Jensen,RV;Guich,SM;Tsai,K;Nuechterlein,KH
维度复杂度反映了对动态过程有贡献的独立变量的数量。从12例精神分裂症患者和11例正常对照组记录的EEG历元进行拉普拉斯滤波，以突出特定于前额叶和顶叶区域的活动，然后导出所得信号的维度复杂性测量。精神分裂症患者脑电波形的复杂性较正常人降低，尤其是左额、右顶叶。这些数据表明，底层的复杂性也降低了。
Dimensional complexity reflects the number of independent variables contributing to a dynamic process. EEG epochs recorded from 12 neuroleptic-free schizophrenic patients and 11 normal control subjects were Laplacian-filtered to highlight activity specific to prefrontal and parietal areas, and dimensional complexity measures of the resulting signals were then derived. Complexity of EEG waveforms generated by schizophrenic patients was depressed relative to that of normal subjects, especially in left frontal and right parietal regions. These data suggest that complexity of underlying is also reduced.