Functional Gastrointestinal Disorders in Obese Patients. The Importance of the Enrollment Source
Functional Gastrointestinal Disorders in Obese Patients. The Importance of the Enrollment Source
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DOI：
10.1007/s11695-015-1679-6
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发表时间：
2015-11-01
期刊：
影响因子：
2.9
通讯作者：
Benamouzig, Robert
中科院分区：
文献类型：
--
作者：
Bouchoucha, Michel;Fysekidis, Marinos;Benamouzig, Robert
肥胖常常与许多功能性胃肠道疾病有关。本研究的目的是根据肥胖患者的体重指数和招募来源评估功能性胃肠道疾病的患病率。596 名肥胖患者（体重指数 (BMI) > 30）填写了标准调查问卷，以评估功能性胃肠道疾病的存在情况。根据罗马III标准和BMI将他们分为四组：OF，功能性胃肠病（FGID）入组的肥胖患者； OO，肥胖管理入组的肥胖患者； MF，FGID 入组的病态肥胖患者； MO，来自肥胖管理入组的病态肥胖患者。使用多变量逻辑回归进行数据分析。在本研究中纳入的 596 名肥胖患者中，183 名 (33%) 抱怨 FGID，而 413 名 (67%) 正在咨询肥胖管理。与OF组相比，OO患者女性患病率较高（P = 0.008）且年龄较小（P < 0.001）。临床上，他们报告反流（P = 0.044）、胸痛（P = 0.004）、肠易激综合征（IBS；P = 0.035）和功能性腹泻（P = 0.030）的发生率较低。与MF组相比，MO患者年龄较大（P = 0.001），BMI较高（P = 0.013），临床上功能性消化不良发生率较高（P = 0.006）。所有组（OF、OO、MF、MO）中都有相似的症状，例如上腹痛、餐后不适、便秘、腹泻、腹胀、腹痛或非特异性肛门直肠疾病。这项研究表明，招募来源解释了肥胖和病态功能性胃肠道疾病患病率的显着和特定差异。 肥胖。应在所有患者中系统地检测所有组中具有相似患病率的症状。
Obesity is frequently associated to many functional gastrointestinal disorders. The aim of the present study was to assess the prevalence of functional gastrointestinal disorders in obese patients, according to their body mass index and their recruitment source.Five hundred ninety-six obese patients (body mass index (BMI) > 30) filled out a standard questionnaire in order to evaluate the presence of functional gastrointestinal disorders. They were divided into four groups according to the Rome III criteria and their BMI: OF, obese patients from functional gastrointestinal disorder (FGID) enrollment; OO, obese patients from obesity management enrollment; MF, morbid obesity patients from FGID enrollment; and MO, morbid obesity patients from obesity management enrollment. Data analysis was performed using multivariate logistic regression.Out of the 596 obese patients included in the present study, 183 (33 %) were complaining of FGIDs, while 413 (67 %) were consulting for obesity management. Compared to the OF group, the OO patients had a higher prevalence of females (P = 0.008) and a younger age (P < 0.001). Clinically, they reported a lower incidence of regurgitation (P = 0.044), of chest pain (P = 0.004), of irritable bowel syndrome (IBS; P = 0.035), and of functional diarrhea (P = 0.030). Compared to the MF group, the MO patients had an older age (P = 0.001), a higher BMI (P = 0.013), and clinically by a high frequency of functional dyspepsia (P = 0.006). There were symptoms that had similar prevalence in all groups (OF, OO, MF, MO) such as epigastric pain, postprandial distress, constipation, diarrhea, bloating, abdominal pain soiling, or nonspecific anorectal disorders.This study has shown that the recruitment source accounted for marked and specific differences in the prevalence of functional gastrointestinal disorders in obesity and morbid obesity. Symptoms with similar prevalence in all groups should be systematically detected in all patients.