Electrophysiology Reveals the Neural Dynamics of Naturalistic Auditory Language Processing: Event-Related Potentials Reflect Continuous Model Updates
Electrophysiology Reveals the Neural Dynamics of Naturalistic Auditory Language Processing: Event-Related Potentials Reflect Continuous Model Updates
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DOI：
10.1523/eneuro.0311-16.2017
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发表时间：
2017-11-01
期刊：
影响因子：
3.4
通讯作者：
Bornkessel-Schlesewsky, Ina
中科院分区：
文献类型：
--
作者：
Alday, Phillip M.;Schlesewsky, Matthias;Bornkessel-Schlesewsky, Ina
最近的趋势是远离基于方差分析的分析，在触手可及的更自然主义和生态有效的设计中对认知的神经生物学进行实验研究。我们使用基于时代的回归的混合效应模型，证明了在自然环境下检测事件相关电位(ERPs)，特别是N400，来研究人类听觉语言加工的神经动力学的可行性。尽管在自然刺激期间，试验之间的差异很大，但我们复制了先前文献中的发现：频率、活力和语序的影响，并发现了以前未被探索的交互影响。这提出了一种新的视角来看待事件相关电位，即作为反映连续刺激的连续调制，而不是锁定在离散事件上的一系列离散且本质上是连续的过程。
The recent trend away from ANOVA-based analyses places experimental investigations into the neurobiology of cognition in more naturalistic and ecologically valid designs within reach. Using mixed-effects models for epoch-based regression, we demonstrate the feasibility of examining event-related potentials (ERPs), and in particular the N400, to study the neural dynamics of human auditory language processing in a naturalistic setting. Despite the large variability between trials during naturalistic stimulation, we replicated previous findings from the literature: the effects of frequency, animacy, and word order and find previously unexplored interaction effects. This suggests a new perspective on ERPs, namely, as a continuous modulation reflecting continuous stimulation instead of a series of discrete and essentially sequential processes locked to discrete events.