Clinical features and prognostic factors of pediatric idiopathic sudden hearing loss from moderate to profound degree
Clinical features and prognostic factors of pediatric idiopathic sudden hearing loss from moderate to profound degree
复制标题
小儿中度至重度特发性突发性耳聋的临床特征及预后因素
DOI：
10.1016/j.amjoto.2021.103027
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发表时间：
2021-04-16
影响因子：
2.5
通讯作者：
Wang, Jing
中科院分区：
文献类型：
--
作者：
Wang, Yi;Ren, Tongli;Wang, Jing
工作背景：儿童突发性感音神经性聋（PISSNHL）在临床上并不少见，但其预后因素尚不清楚。目的：探讨PISSNHL的临床和听力学特征与预后的关系。材料和方法：对76例年龄小于19岁的PISSNHL患者的临床和听力学特征以及可能的预后因素进行了回顾性评价。结果：中度听力损失9例，重度听力损失21例，重度听力损失46例。在5种类型的听力图中，上升型占3.9%，下降型占11.8%，平坦型占25.0%，极深型占55.3%，凹型占3.9%。根据Siegel标准的回收率为55.3%。康复组与康复不良组在年龄、性别、听力损失偏侧性、治疗开始时间、伴随症状等方面差异无统计学意义（p > 0.05）。单因素分析显示，两组的初始听力水平和听力图类型有显著性差异（p < 0.001），而多因素分析显示，只有初始听力水平有显著性差异（p = 0.046）。结论及意义：PISSNHL的预后主要与发病时的初始听力有关。初始听力水平大于80 dB是一个不良的预后因素。
Background: The pediatric idiopathic sudden sensorineural hearing loss (PISSNHL) is not rare in the clinics, however, the prognostic factors of PISSNHL are still unclear. Objectives: To investigate the clinical and audiologic characteristics associated with prognosis in PISSNHL. Material and methods: Clinical and audiological characteristics and possible prognostic factors were retrospectively evaluated in 76 PISSNHL patients aged less than 19 years. Results: Hearing loss was moderate in nine patients, severe in 21 patients, profound in 46 patients. Among five types of audiogram, 3.9% were classified as ascending, 11.8% as descending, 25.0% as flat, 55.3% as profound, and 3.9% as concave. The recovery rate according to Siegel's criteria was 55.3%. There was no significant difference between the recovery group and the poor recovery group in terms of age, sex, laterality of hearing loss, the onset of treatment, and accompanying symptoms (p > 0.05). The initial hearing levels and the audiogram type were significantly different in the two groups (p < 0.001) according to univariate analysis, while only the initial hearing level was significantly different (p = 0.046) according to multivariate analysis. Conclusions and significance: Prognosis of PISSNHL was mainly related to initial hearing at onset. An initial hearing level greater than 80 dB was a poor prognostic factor.