MEAL PATTERN DURING THE TRANSIENT HYPOPHAGIA OF RATS SWITCHED FROM A HIGH-FAT TO A HIGH-CARBOHYDRATE DIET
MEAL PATTERN DURING THE TRANSIENT HYPOPHAGIA OF RATS SWITCHED FROM A HIGH-FAT TO A HIGH-CARBOHYDRATE DIET
复制标题
DOI：
10.1006/appe.1995.0050
复制
发表时间：
1995-10-01
期刊：
影响因子：
5.4
通讯作者：
SCHARRER, E
中科院分区：
文献类型：
--
作者：
DELPRETE, E;SCHARRER, E
当大鼠从无碳水化合物的高脂肪（HF）饮食转换为等热量的高碳水化合物（HC）饮食时，在持续约1周的短暂摄食不足期间研究膳食模式。在HF/HC饮食转换后，通过减少膳食量抑制了自主摄食量，而膳食频率保持不受影响。因此，进食HC饮食的HF大鼠的饱腹感比率增加。观察到HF/HC转换后的第一餐与随后的餐不同，尚未减少，这表明条件反射与转换导致的餐量减少有关。饮食转换后约1周，大鼠的喂养模式已调整为接受HF饮食的大鼠。与HF/HC转换不同，HC/HF转换并没有减少累积的食物摄入量，但在第一天减少了膳食量并增加了膳食频率。有人建议，短暂的减少膳食量和增加饱腹感比以下的HF/HC饮食开关部分原因是从一个相对较高的吸收后饱腹感的葡萄糖相关的葡萄糖处置率低，在以前的工作中发现在这种条件下的潜力。也可能涉及碳水化合物的胃肠道清除率一过性降低。(C)1995年学术出版社
Meal pattern was investigated during the transient hypophagia lasting about 1 week when rats are switched from a carbohydrate-free high fat (HF) diet to an isocaloric high carbohydrate (HC) diet. After the HF/HC diet switch, voluntary food intake was suppressed through reduction of meal size with meal frequency remaining unaffected. Thus, the satiety ratio was increased in HF rats ingesting the HC diet. The observation that the first meal after the HF/HC switch, unlike the following meals, was not yet diminished, suggests that conditioning is involved in the reduction of meal size resulting from the switch. About 1 week after the dietary switch, the feeding pattern of rats had adjusted to that of rats receiving the HF diet. Unlike the HF/HC switch, the HC/HF switch did not reduce cumulative food intake, but decreased meal size and increased meal frequency during the first day. It is suggested that the transient decrease in meal size and increase in satiety ratio following the HF/HC diet switch arises partly from a relatively high postabsorptive satiating potency of glucose related to a low rate of glucose disposal found in previous work under such conditions. A transiently reduced gastrointestinal clearance of carbohydrate may also be involved. (C) 1995 Academic Press Limited