The origin of four squirrel monkey cell lines established by karyotype analysis.
The origin of four squirrel monkey cell lines established by karyotype analysis.
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通过核型分析建立的四种松鼠猴细胞系的起源。
DOI：
10.1159/000056995
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发表时间：
2001
期刊：
影响因子：
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通讯作者：
Tuck-Muller,CM
中科院分区：
文献类型：
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作者：
Scammell,JG;Wright,JL;Tuck-Muller,CM
松鼠猴是一种新热带灵长类动物属，广泛用于生物医学研究，但包括个体物种和亚种，它们对实验扰动的反应不同。利用15号和16号染色体的gtg带带模式，确定了来自遗传背景未知的松鼠猴（DPSO 114/74、SqMkLu/68和7603830）的3株肺成纤维细胞系的来源，并证实了最近在圭亚那松鼠猴中建立的一株淋巴母细胞系（GSML）的来源。DPSO 114/74细胞来自秘鲁松鼠猴，SqMkLu/68细胞来自玻利维亚松鼠猴，7603830细胞来自秘鲁/玻利维亚杂交。染色体分析证实GSML细胞来自圭亚那松鼠猴。
The squirrel monkey is a neotropical primate genus which is widely used in biomedical research but includes individual species and subspecies that respond differently to experimental perturbations. GTG-banding patterns of chromosomes 15 and 16, which are distinct among different squirrel monkey species and subspecies, were used to determine the origin of three lung fibroblast cell lines from squirrel monkeys of unknown genetic background (DPSO 114/74, SqMkLu/68, and 7603830) and to confirm the origin of a lymphoblast cell line (GSML) recently established from Guyanese squirrel monkey. DPSO 114/74 cells are from Peruvian squirrel monkey, SqMkLu/68 cells are Bolivian squirrel monkey, and 7603830 cells are from a Peruvian/Bolivian hybrid. Chromosome analysis of GSML cells confirmed that they are from Guyanese squirrel monkey.