Letter and category fluency in schizophrenic patients: a meta-analysis
Letter and category fluency in schizophrenic patients: a meta-analysis
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DOI：
10.1016/s0920-9964(02)00282-7
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发表时间：
2003-11-01
影响因子：
4.5
通讯作者：
Goldberg, TE
中科院分区：
文献类型：
--
作者：
Bokat, CE;Goldberg, TE
精神分裂症患者通常在语义和字母流畅性任务上表现出障碍，但这些测试可能需要微妙不同的认知处理：基于音系或正字法的词汇搜索或基于维度或属性的语义网络组织的语义搜索。这两个任务之间的表现差异可能暗示了缺陷是否涉及访问或遍历语义系统中的连接的困难，而不是基于语言单位的困难。在本荟萃分析中，我们回顾了13项研究（N = 915），试图澄清精神分裂症患者是否在语义流畅性方面存在差异受损。分析结果表明，精神分裂症患者在类别流畅性方面存在不成比例的缺陷（语义流畅性d = 1.23，字母流畅性d = 1.01，加权d的置信区间重叠最小），这表明语义系统的妥协可能存在于精神分裂症中，并可能在该患者群体中表现出的症状异常中发挥作用。(C) 2002 Elsevier Science B.V.版权所有
Patients with schizophrenia typically demonstrate impairments on semantic and letter fluency tasks but it is possible that these tests demand subtly different cognitive processing: a lexical search based on phonology or orthography or a semantic search based on organization of semantic networks by dimension or attribute. Differences in the performance between these two tasks may imply whether deficits involve difficulties in accessing or traversing connectivities in the semantic system, as opposed to those based on linguistic units. In this meta-analysis, we reviewed 13 studies (N = 915) in an attempt to clarify whether schizophrenic patients are in fact differentially impaired in semantic fluency. Results from analyses indicated that schizophrenic patients are disproportionately deficient in category fluency (d = 1.23 for semantic and 1.01 for letter fluency with minimal overlap of confidence intervals of weighted d's) suggesting that compromises the semantic system may be present in schizophrenia and perhaps play a role in the symptomatic anomalies exhibited in this patient population. (C) 2002 Elsevier Science B.V. All rights reserved.