Glutamate in the Immune System: Glutamate Receptors in Immune Cells, Potent Effects, Endogenous Production and Involvement in Disease
Glutamate in the Immune System: Glutamate Receptors in Immune Cells, Potent Effects, Endogenous Production and Involvement in Disease
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DOI：
10.1007/978-3-7091-0888-8_4
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发表时间：
2012-01-01
期刊：
影响因子：
--
通讯作者：
Levite, Mia
中科院分区：
文献类型：
--
作者：
Ganor, Yonatan;Levite, Mia
谷氨酸是一种氨基酸，是脊椎动物神经系统中主要的兴奋性神经递质。谷氨酸参与认知、记忆、学习等大脑正常功能的大多数方面，也在中枢神经系统的发育中发挥重要作用，包括突触的诱导和消除，细胞的迁移、分化和死亡。谷氨酸还在心脏、肾脏、肠、肺、肌肉、肝脏、卵巢、睾丸、骨骼、胰腺以及肾上腺、垂体和松果体等周围器官和组织中发挥信号作用。
Glutamate, an amino acid, is the principal excitatory neurotransmitter within the vertebrate nervous system. Glutamate is involved in most aspects of normal brain function including cognition, memory and learning, and also plays major roles in the development of the central nervous system, including synapse induction and elimination, and cell migration, differentiation and death. Glutamate further plays a signaling role in peripheral organs and tissues, such as the heart, kidney, intestine, lungs, muscles, liver, ovary, testis, bone, pancreas and the adrenal, pituitary and pineal glands.