A re-examination of within-mouth correlations of attachment level and of change in attachment level.
A re-examination of within-mouth correlations of attachment level and of change in attachment level.
复制标题
重新检查依恋水平和依恋水平变化的口内相关性。
DOI：
10.1111/j.1600-051x.1988.tb01594.x
复制
发表时间：
1988
影响因子：
6.7
通讯作者：
Goodson,JM
中科院分区：
文献类型：
--
作者：
Fleiss,JL;Wallenstein,S;Chilton,NW;Goodson,JM
使用来自Forsyth牙科中心的数据集，包括对22名患者1年内牙周附着水平的重复测量，我们在4个时间点（基线、1个月、6个月和9个月）对3个测量单位（部位、牙齿和象限）进行相关性分析。获得横截面测量和基线变化的类内相关系数值。结果均为正数，且数值显著，表明依恋水平的测量值与同一口内依恋水平变化的测量值呈正相关。因此，在牙周病的比较临床试验中，以部位而不是患者作为统计分析的单位，往往会产生低估的标准误差和夸大的统计意义。
Using a data set from the Forsyth Dental Center consisting of repeated measurements of periodontal attachment level on 22 patients over 1 year, we performed correlation analyses at 4 time points (baseline, 1 month, 6 months and 9 months) for 3 units of measurement (sites, teeth and quadrants). Values of the intraclass correlation coefficient were obtained for the cross‐sectional measurements and for changes from baseline. The values were positive and often of appreciable magnitude, indicating that measurements of attachment level and of change in attachment level within the same mouth are positively correlated. Taking sites rather than patients as the units of statistical analysis in comparative clinical trials in periodontology will therefore tend to produce underestimated standard errors and overstated statistical significance.