Body composition during the first 2 years of life: An updated reference
Body composition during the first 2 years of life: An updated reference
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DOI：
10.1203/00006450-200005000-00004
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发表时间：
2000-05-01
影响因子：
3.6
通讯作者：
Ellis, KJ
中科院分区：
文献类型：
--
作者：
Butte, NF;Hopkinson, JM;Ellis, KJ
标准的身体组成在第一个2年的生活是来自一项前瞻性研究的76名儿童。我们提出了I）无脂肪质量（FFM）及其组成部分，和脂肪质量（FM），2）增量增长率划分为化学成分，和3）年龄特异性和性别特异性常数转换为FFM的化学和物理成分的儿童在生命的第一个2年。采用多组分模型，根据测量的全身水（TBW），全身钾（TBK）和骨矿物质含量（BMC），估计FFM和FM在0.5，3，6，9，12，18和24月龄，TBW测定氘稀释，TBK测定全身计数，和BMC双能X线吸收法。在0.5-18个月之间，男孩的FFM高于女孩（p小于或等于0.05）。在0.5和3-6个月之间，FM百分比平均从13%增加到31%，然后逐渐下降。在6个月和9个月时，女孩的FM百分比显著高于男孩（p小于或等于0.02）。实况调查的组成部分按百分比计算随年龄而变化（p = 0.001），但不随性别而变化。FFM的蛋白质含量随着年龄的增长而逐渐增加，而TBW则下降（p = 0.001）。作为FFM的百分比，在0.5和24个月之间，男孩的骨矿物质从2.0%增加到3.4%，女孩从2.1%增加到3.3%（p = 0.001）。FFM的密度和钾含量随着年龄的增长而逐渐增加（p = 0.001）。这些规范性身体成分数据提供了最新的参考，可用于评估代表混合喂养组的儿科人群在出生后2年内的正常生长和营养状况。
Normative body composition during the first 2 y of life was derived from a prospective study of 76 children. We present I) fat free mass (FFM) and its components, and fat mass (FM), 2) incremental growth rates partitioned into chemical components, and 3) age-specific and gender-specific constants for converting chemical and physical components into FFM for children during the first 2 y of life. A multicomponent model based on measurements of total body water (TBW), total body potassium (TBK) and bone mineral content (BMC) was used to estimate FFM and FM at 0.5, 3, 6, 9, 12, 18, and 24 mo of age, TBW was determined by deuterium dilution, TBK by whole body counting, and BMC by dual energy x-ray absorptiometry. FFM was higher in boys than girls between 0.5-18 mo of age (p less than or equal to 0.05). Percent FM increased on average from 13 to 31% between 0.5 and 3-6 mo, and then gradually declined. Percent FM was significantly higher in girls than in boys at 6 and 9 mo of age (p less than or equal to 0.02). The components of FFM on a percentage basis changed with age (p = 0.001), but not gender. The protein content of FFM increased gradually with age, while TBW declined (p = 0.001). As a percentage of FFM, osseous mineral increased from 2.0 to 3.4% in boys and from 2.1 to 3.3% in girls between 0.5 and 24 mo (p = 0.001). Density and potassium content of FFM increased gradually with age (p = 0.001). These normative body composition data provide an updated reference upon which to assess normal growth and nutritional status of pediatric populations representative of mixed feeding groups during the first 2 y of life.