Pulmonary blastoma. A case report.
Pulmonary blastoma. A case report.
复制标题
肺母细胞瘤。
作者：
S. Yokoyama;Y. Hayashida;J. Nagahama;K. Kashima;I. Nakayama;K. Tanaka;T. Hadama;M. Mizuki
肺母细胞瘤发生于一位71岁的男性。支气管刷毛标本可见大量上皮细胞和少量间充质细胞团。上皮细胞圆形至卵圆形，比普通腺癌细胞更均匀、更小。细胞核质比增大，染色质分布均匀，核仁不明显。间充质细胞团呈明显的多细胞性，由小而短的梭形细胞组成，细胞核深染。虽然通过细胞学正确诊断肺母细胞瘤非常困难，但当观察到小的非鳞状肿瘤细胞时，特别是与小而短的纺锤状细胞相关时，应考虑肺母细胞瘤的可能性，使人联想到间充质起源。
Pulmonary blastoma occurred in a 71-year-old man. Bronchial brushing specimens showed numerous epithelial cells and only a few mesenchymal cell clusters. The epithelial cells were round to oval, more uniform and smaller than ordinary adenocarcinoma cells. The nuclear:cytoplasmic ratio of these cells was increased, with an even chromatin distribution, and nucleoli were inconspicuous. Mesenchymal cell clusters were markedly hypercellular and consisted of small and short spindle-shaped cells with hyperchromatic nuclei. Although it is very difficult to diagnose pulmonary blastoma correctly by cytology, the possibility of pulmonary blastoma should be considered when small, nonsquamous neoplastic cells are observed, particularly in association with small and short spindle-shaped cells reminiscent of mesenchymal origin.