Radical scavenging activity of methanol leaf extracts of Orthosiphon stamineus
Radical scavenging activity of methanol leaf extracts of Orthosiphon stamineus
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DOI：
10.1080/13880200490902572
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发表时间：
2004-12-01
影响因子：
3.8
通讯作者：
Sadikun, A
中科院分区：
文献类型：
--
作者：
Akowuah, GA;Zhari, I;Sadikun, A
采用1，1-二苯基-2-苦基肼（DPPH）自由基和超氧阴离子自由基清除率测定了马来西亚不同地区栽培的野管草（Orthosiphon stamineus Benth）甲醇提取物的抗氧化活性。结果表明，甲醇提取物对自由基和超氧阴离子的清除活性分别为62.82%~ 92.34%和53.29%~ 75.88%。甲醇提取物具有抗氧化活性，其抗氧化能力与纯槲皮素相当，高于广泛使用的合成抗氧化剂丁基羟基茴香醚（BHA）。不同产地的地管草甲醇叶提取物的主要酚类物质的紫外和高效液相色谱指纹图谱定性相似。
The antioxidant activity of methanol extracts of Orthosiphon stamineus Benth (Lamiaceae), cultivated in different regions of Malaysia, was determined by measuring the scavenging effect on 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical and on superoxide anion. The results showed a variation in free-radical and superoxide-anion scavenging activities of the methanol extracts ranging from 62.82 to 92.34% and 53.29 to 75.88%, respectively. Methanol extract was active, and its antioxidative potency was comparable to that of pure quercetin and higher than that of the widely used synthetic antioxidant butylated hydroxylanisole (BHA). The UV and HPLC chromatographic fingerprints of the major phenolics were qualitatively similar for all the methanol leaf extracts of Orthosiphon stamineus from various locations.