Amnesic effects of bilateral lesions placed in the hyperstriatum ventrale of the chick after imprinting
Amnesic effects of bilateral lesions placed in the hyperstriatum ventrale of the chick after imprinting
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印记后雏鸡上纹状体腹侧双侧病变的遗忘效应
DOI：
10.1007/bf00239568
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发表时间：
2004
影响因子：
2
通讯作者：
Patrick Bateson
中科院分区：
文献类型：
--
作者：
Brian J. McCabe;José Cipolla;Gabriel Horn;Patrick Bateson
本研究的目的是调查是否双边病变的一部分腹侧纹状体（IMHV）损害保留，如果他们被放置后，小鸡已被印记。将家鸡孵化并在黑暗中饲养，并在孵化后22 h开始暴露于印记（训练）刺激2 h。然后将小鸡麻醉，并将双侧病变置于IMHV（N = 16）鸟、副纹状体上（HA; N = 16）或大脑半球的外侧部分（LCA; N = 16）。48只假手术鸡作为对照。将小鸡放回黑暗的孵化器中，并且在手术后15-20小时，测量它们对训练刺激和第二新刺激的接近。对照组和HA和LCA损伤的雏鸡表现出对训练刺激的强烈偏好，因此保持水平较高。这三个实验组的偏好没有显着差异。IMHV损伤组的平均偏好性显著低于假手术对照组（P<0.01）和HA损伤组（P<0.05）。因此，IMHV的双侧病变选择性地损害了通过印记获得的偏好的保留。这种损害不太可能是感官处理或运动表现缺陷的非特异性后果，因为四组在以下方面没有差异：（i）准确地啄食摇摆珠所需的时间，（ii）啄食小米种子的准确性和（iii）涉及热强化的同时视觉辨别任务的表现。
The purpose of this study was to investigate whether bilateral lesions to a part of the hyperstriatum ventrale (IMHV) impair retention if they are placed after chicks have been imprinted. Domestic chicks were hatched and reared in darkness and exposed to an imprinting (training) stimulus for 2 h commencing ≃ 22 h post hatch. The chicks were then anaesthetised and bilateral lesions placed in IMHV (N = 16) birds, hyperstriatum accessorium (HA; N = 16) or the lateral part of the cerebral hemispheres (LCA; N = 16). Forty-eight sham-operated chicks served as controls. Chicks were returned to the dark incubator, and, 15–20 h after the operation, their approach towards the training stimulus and to a second novel stimulus was measured. The controls and the chicks with lesions in HA and LCA showed a strong preference for the training stimulus and hence a high level of retention. The preferences of these three experimental groups did not differ significantly from one another. The mean preference of chicks with lesions in IMHV was significantly less than that of the sham-operated controls (P<0.01) and of chicks lesioned in HA (P<0.05). Bilateral lesions to IMHV therefore selectively impair retention of a preference acquired through imprinting. This impairment is unlikely to be a non-specific consequence of defective sensory processing or motor performance because the four groups did not differ from each other in (i) the time taken accurately to peck a rocking bead, (ii) the accuracy of pecking millet seeds and (iii) the performance of a simultaneous visual discrimination task involving heat reinforcement.