CYCLIN - A PROTEIN SPECIFIED BY MATERNAL MESSENGER-RNA IN SEA-URCHIN EGGS THAT IS DESTROYED AT EACH CLEAVAGE DIVISION
CYCLIN - A PROTEIN SPECIFIED BY MATERNAL MESSENGER-RNA IN SEA-URCHIN EGGS THAT IS DESTROYED AT EACH CLEAVAGE DIVISION
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DOI：
10.1016/0092-8674(83)90420-8
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发表时间：
1983-01-01
期刊：
影响因子：
64.5
通讯作者：
HUNT, T
中科院分区：
文献类型：
--
作者：
EVANS, T;ROSENTHAL, ET;HUNT, T
海胆 Arbacia punctulata 胚胎的分裂由 8 个非常快速的分裂组成，需要持续的蛋白质合成来维持它们。这种合成是由储存的母体 mRNA 编程的，它编码 3 或 4 种特别丰富的蛋白质，这些蛋白质的合成在未受精卵中几乎检测不到。每次细胞分裂时，其中一种蛋白质就会被破坏。海胆 Lytechinus pictus 的卵和北蛤 Spisula Solidissima 的卵母细胞也含有蛋白质，这些蛋白质仅在受精后开始产生，并在细胞分裂周期的某些时刻被破坏。这些蛋白质称为细胞周期蛋白。
Cleavage in embryos of the sea urchin Arbacia punctulata consists of 8 very rapid divisions that require continual protein synthesis to sustain them. This synthesis is programmed by stored maternal mRNA, which code for 3 or 4 particularly abundant proteins whose synthesis is barely if at all detectable in the unfertilized egg. One of these proteins is destroyed every time the cells divide. Eggs of the sea urchin Lytechinus pictus and oocytes of the surf clam Spisula solidissima also contain proteins that only start to be made after fertilization and are destroyed at certain points in the cell division cycle. These proteins are called the cyclins.