PSEUDOGENE STRUCTURE IN 5S-DNA OF XENOPUS-LAEVIS
PSEUDOGENE STRUCTURE IN 5S-DNA OF XENOPUS-LAEVIS
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DOI：
10.1016/0092-8674(77)90189-1
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发表时间：
1977-01-01
期刊：
影响因子：
64.5
通讯作者：
BROWNLEE, GG
中科院分区：
文献类型：
--
作者：
JACQ, C;MILLER, JR;BROWNLEE, GG
X. laevis编码卵母细胞型5S RNA，由约700个碱基对的串联重复单位的许多拷贝组成。除了基因外，每个单元还包含一个假基因。假基因部分测序，似乎是一个几乎完美的重复的101个残基的基因。在DNA的+链（或H链）中，重复单元中各组分的顺序为（5“）长间隔区、sbd基因、sbd连接子、sbd假基因（3”）。并对假基因的可能功能进行了讨论。
The 5S DNA of X. laevis, coding for oocyte-type 5S RNA, consists of many copies of a tandemly repeated unit of about 700 base pairs. Each unit contains a pseudogene in addition to the gene. The pseudogene was partly sequenced and appears to be an almost perfect repeat of 101 residues of the gene. The order of components in the repeat unit is (5'') long spacer.sbd.gene.sbd.linker.sbd.pseudogene (3'') in the + strand (or H strand) of the DNA. The possible function of the pseudogene is discussed.