Determinants of vaccine hesitancy in Quebec: a large population-based survey
Determinants of vaccine hesitancy in Quebec: a large population-based survey
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DOI：
10.1080/21645515.2019.1603563
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发表时间：
2019-05-15
影响因子：
4.8
通讯作者：
Gagneur, Arnaud
中科院分区：
文献类型：
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作者：
Guay, Maryse;Gosselin, Virginie;Gagneur, Arnaud
目标：疫苗犹豫是一个全球现象，需要加以衡量和解决。本研究旨在确定一个大的区域人群中的疫苗犹豫的决定因素。方法：在魁北克的东部乡镇地区的随机数字样本进行结构化的电话调查。除了社会经济信息外，受访者还被问及有关免疫接种、医疗咨询、健康状况和生活习惯的知识和信念等几个健康主题。根据年龄、性别和地区对数据进行加权。将单变量分析中具有统计学意义的变量引入多变量logistic回归模型，以确定疫苗犹豫的独立因素（校正比值比[aOR]和95%置信区间）。结果：共进行了8，737次访谈（参与率为48.3%）。在所有受访者中，32.2%的人对疫苗犹豫不决。有几种信念与疫苗犹豫有着显著的联系：认为孩子接种了太多的疫苗（aOR = 2.72; 2.32-3.18），认为健康的生活方式可以消除接种疫苗的需要（aOR = 2.48; 2.09-2.93），以及认为使用替代医学实践可以消除对疫苗接种的需要（aOR = 1.39; 1.16-1.68）。与疫苗犹豫相关的其他决定因素包括咨询过按摩治疗师（aOR = 2.34; 1.46-3.75）、未接种流感疫苗（aOR = 1.80; 1.49-2.16）、有低（
Objectives: Vaccine hesitancy is a global phenomenon that needs to be measured and addressed. This study aimed to identify the determinants of vaccine hesitancy among a large regional population. Methods: A structured telephone survey was administered to a random digit sample in Quebec's Eastern Townships region. In addition to socioeconomic information, respondents were asked questions on several health topics such as knowledge and beliefs about immunization, medical consultations, health status, and life habits. Data were weighted according to age, sex, and territories. Statistically significant variables in the univariate analysis were introduced into a multivariate logistic regression model to determine independent factors for vaccine hesitancy (adjusted odds ratios [aOR] and 95% confidence intervals). Results: A total of 8,737 interviews were conducted (participation rate 48.3%). Among all respondents, 32.2% were vaccine-hesitant. Several beliefs were significantly associated with vaccine hesitancy: belief that children receive too many vaccines (aOR = 2.72; 2.32-3.18), belief that a healthy lifestyle can eliminate the need for vaccination (aOR = 2.48; 2.09-2.93), and belief that the use of alternative medicine practices can eliminate the need for vaccination (aOR = 1.39; 1.16-1.68). Other determinants associated with vaccine hesitancy were having consulted a massage therapist (aOR = 2.34; 1.46-3.75), not being vaccinated against influenza (aOR = 1.80; 1.49-2.16), having a low (