Array Designer: automated optimized array design for functional near-infrared spectroscopy.
Array Designer: automated optimized array design for functional near-infrared spectroscopy.
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DOI：
10.1117/1.nph.5.3.035010
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发表时间：
2018-07
期刊：
影响因子：
5.3
通讯作者：
Cooper RJ
中科院分区：
文献类型：
--
作者：
Brigadoi S;Salvagnin D;Fischetti M;Cooper RJ
每个源和检测器“光极”在头皮上的位置以及它们的相对间隔决定了每个功能性近红外光谱（fNIRS）通道对底层皮层的灵敏度。因此，为可用的源和检测器选择合适的头皮位置对每个fNIRS实验都至关重要。目前，用户手动执行该任务是标准的做法;选择他们认为是头皮上放置他们的视杆的最佳位置，以便对给定的皮层感兴趣区域（ROI）进行采样。这个过程是困难的，耗时的，并且非常主观。在这里，我们提出了一个工具，阵列设计器，它能够自动设计优化的fNIRS阵列给定用户定义的ROI和可用的fNIRS设备的某些功能。重要的是，Array Designer方法是可推广的，将适用于几乎任何受试者人群或fNIRS器械。我们描述和验证的算法方法，通过运行阵列设计问题的多个模拟在一个现实的解剖模型的阵列设计器的基础。我们相信Array Designer有可能结束手动阵列设计的需求，从而节省研究人员的时间，提高fNIRS数据质量，并促进整个领域的标准化。
The position of each source and detector “optode” on the scalp, and their relative separations, determines the sensitivity of each functional near-infrared spectroscopy (fNIRS) channel to the underlying cortex. As a result, selecting appropriate scalp locations for the available sources and detectors is critical to every fNIRS experiment. At present, it is standard practice for the user to undertake this task manually; to select what they believe are the best locations on the scalp to place their optodes so as to sample a given cortical region-of-interest (ROI). This process is difficult, time-consuming, and highly subjective. Here, we propose a tool, Array Designer, that is able to automatically design optimized fNIRS arrays given a user-defined ROI and certain features of the available fNIRS device. Critically, the Array Designer methodology is generalizable and will be applicable to almost any subject population or fNIRS device. We describe and validate the algorithmic methodology that underpins Array Designer by running multiple simulations of array design problems in a realistic anatomical model. We believe that Array Designer has the potential to end the need for manual array design, and in doing so save researchers time, improve fNIRS data quality, and promote standardization across the field.