Genomic cloud computing: legal and ethical points to consider.
Genomic cloud computing: legal and ethical points to consider.
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DOI：
10.1038/ejhg.2014.196
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发表时间：
2015-10
期刊：
影响因子：
--
通讯作者：
Knoppers BM
中科院分区：
文献类型：
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作者：
Dove ES;Joly Y;Tassé AM;Public Population Project in Genomics and Society (P3G) International Steering Committee;International Cancer Genome Consortium (ICGC) Ethics and Policy Committee;Knoppers BM
21世纪数据密集型基因组科学面临的最大挑战是开发庞大的计算机基础设施和先进的软件工具，为生物医学研究和临床实践执行基因组数据集的综合分析。研究人员越来越多地将云计算作为整合基因组学、系统生物学和生物医学数据挖掘数据的解决方案，以及分析数据以解决生物医学问题的方法。尽管云计算提供了一些好处，比如更低的成本和更高的效率，但它也引发了法律和道德问题。在本文中，我们基于对几个公开可用的云服务提供商的服务条款的初步审查，讨论了三个需要考虑的关键点（数据控制；数据安全、机密性和传输；以及问责制）。基因组研究组织在就在大型商业云服务提供商的服务器上存储基因组数据的法律安排进行谈判时，应该牢记这些“需要考虑的要点”。勤勉的基因组云计算意味着利用安全标准和评估流程作为保护数据的一种手段，并需要研究人员在保护其本地基础设施时始终考虑的许多相同的良好实践。
The biggest challenge in twenty-first century data-intensive genomic science, is developing vast computer infrastructure and advanced software tools to perform comprehensive analyses of genomic data sets for biomedical research and clinical practice. Researchers are increasingly turning to cloud computing both as a solution to integrate data from genomics, systems biology and biomedical data mining and as an approach to analyze data to solve biomedical problems. Although cloud computing provides several benefits such as lower costs and greater efficiency, it also raises legal and ethical issues. In this article, we discuss three key ‘points to consider' (data control; data security, confidentiality and transfer; and accountability) based on a preliminary review of several publicly available cloud service providers' Terms of Service. These ‘points to consider' should be borne in mind by genomic research organizations when negotiating legal arrangements to store genomic data on a large commercial cloud service provider's servers. Diligent genomic cloud computing means leveraging security standards and evaluation processes as a means to protect data and entails many of the same good practices that researchers should always consider in securing their local infrastructure.