F-18FDG-positron emission tomographic scanning and Wegener's granulomatosis
F-18FDG-positron emission tomographic scanning and Wegener's granulomatosis
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DOI：
10.1097/00003072-200210000-00004
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发表时间：
2002-10-01
影响因子：
10.6
通讯作者：
Hain, SF
中科院分区：
文献类型：
--
作者：
Beggs, AD;Hain, SF
韦格纳肉芽肿病是一种坏死性肉芽肿性血管炎，主要影响上呼吸道、肺和肾脏。假设自身免疫机制在该疾病的病理生理学中发挥作用。由于葡萄糖代谢的差异，F-18 氟脱氧葡萄糖-正电子发射断层扫描通常用于区分良性和恶性疾病。作者介绍了韦格纳肉芽肿病例，其中 F-18 氟脱氧葡萄糖-正电子发射断层扫描产生假阳性结果。
Wegener's granulomatosis is a necrotizing granulomatous vasculitis that mainly affects the upper airways, lungs, and kidneys. Autoimmune mechanisms are hypothesized to play a role in the pathophysiology of the disease. F-18 fluorodeoxyglucose-positron emission tomographic scanning is normally used to differentiate benign from malignant disease as a result of differences in glucose metabolism. The authors present a case of Wegener's granulomatosis in which F-18 fluorodeoxyglucose-positron emission tomographic scanning yielded a false-positive result.