THE CHOLEDOCHO‐PANCREATICO‐DUCTAL JUNCTION IN INFANTILE OBSTRUCTIVE JAUNDICE DISEASES
THE CHOLEDOCHO‐PANCREATICO‐DUCTAL JUNCTION IN INFANTILE OBSTRUCTIVE JAUNDICE DISEASES
复制标题
婴儿梗阻性黄疸疾病中的胆总管-胰腺-导管连接处
DOI：
10.1111/j.1440-1827.1980.tb01315.x
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发表时间：
1980
影响因子：
2.2
通讯作者：
K. Hashimoto
中科院分区：
文献类型：
--
作者：
K. Suda;T. Miyano;K. Hashimoto
对婴儿梗阻性黄疸病的尸检病例和对照病例进行了胆总管和主胰管如何开口进入十二指肠的组织病理学研究。所谓“共同通道”地层类型（Ⅲ型）分为两种类型： Ⅲa型胆总管与胰管交界处位于十二指肠粘膜或粘膜下层，Ⅲb型位于十二指肠固有肌层下方。 28例先天性胆道闭锁病例中，17例为IIIb型，2例先天性胆总管囊肿病例为IIIb型，对照病例均为IIIa型。在 IIIb 型病例中，发育良好的括约肌位于粘膜下层，并且在两条导管连接后包围了共同通道，这表明两条导管自由连通的可能性。由于胰管的管内压力通常高于胆管，胰液可能会反流入胆管。胆总管胰管连接异常被认为是引起婴儿梗阻性黄疸病的致病因素。
A histopathological study on how the common bile duct and main pancreatic duct open into the duodenum was performed on autopsied cases of infantile obstructive jaundice diseases, and control cases. The so‐called “common channel” formation type (Type III) was divided into two types; the junction of the common bile duct and the pancreatic duct was situated in the mucosal or submucosal layer of the duodenum in type IIIa and the junction below the propria muscularis of the duodenum in type IIIb. Type IIIb was identified in 17 out of 28 cases in congenital biliary atresia and in 2 cases of congenital choledochal cyst, while the control cases all belonged to type IIIa. In cases of type IIIb the well‐developed sphincter muscle was located in the submucosal layer and it surrounded the common channel after joining of both ducts suggesting the possibility of free communication of both ducts. As the intraductal pressure of pancreatic duct is normally higher than that of the bile duct, reflux of pancreatic juice may occur into the bile duct. Abnormal choledocho‐pancreaticoductal junction was suggested to be a pathogenic factor which causes infantile obstructive jaundice diseases.