Acute exacerbation of COPD: is it the "stroke of the lungs"?
Acute exacerbation of COPD: is it the "stroke of the lungs"?
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DOI：
10.2147/copd.s106160
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发表时间：
2016
影响因子：
2.8
通讯作者：
Tzanakis N
中科院分区：
文献类型：
--
作者：
Hillas G;Perlikos F;Tzanakis N
慢性阻塞性肺疾病（COPD）是世界范围内发病率和死亡率的五大主要原因之一。尽管世界范围内的医疗保健努力，成本和医学研究，COPD的数字表明死亡率不断上升的趋势。这与其他主要死亡原因相反，如肿瘤，事故和心血管疾病。影响COPD相关死亡率的主要因素是COPD急性加重（AECOPD）。急性加重和合并症导致个体患者的总体严重程度。尽管医生和患者自己低估了AECOPD，但AECOPD是疾病过程中真正具有破坏性的事件，类似于冠心病患者的急性心肌梗死。在这篇综述中，我们重点关注支持AECOPD是“肺中风”的证据。AECOPD可以被视为：半结肠或疾病的完全停止期，触发灾难性级联反应，通常是复发性和压倒性事件，作为杀手，需要紧急治疗。
Chronic obstructive pulmonary disease (COPD) is one of the top five major causes of morbidity and mortality worldwide. Despite worldwide health care efforts, costs, and medical research, COPD figures demonstrate a continuously increasing tendency in mortality. This is contrary to other top causes of death, such as neoplasm, accidents, and cardiovascular disease. A major factor affecting COPD-related mortality is the acute exacerbation of COPD (AECOPD). Exacerbations and comorbidities contribute to the overall severity in individual patients. Despite the underestimation by the physicians and the patients themselves, AECOPD is a really devastating event during the course of the disease, similar to acute myocardial infarction in patients suffering from coronary heart disease. In this review, we focus on the evidence that supports the claim that AECOPD is the “stroke of the lungs”. AECOPD can be viewed as: a Semicolon or disease’s full-stop period, Triggering a catastrophic cascade, usually a Relapsing and Overwhelming event, acting as a Killer, needing Emergent treatment.