Effect of intravenous streptokinase on acute myocardial infarction: pooled results from randomized trials.
Effect of intravenous streptokinase on acute myocardial infarction: pooled results from randomized trials.
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DOI：
10.1056/nejm198211043071904
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发表时间：
1982-11
期刊：
影响因子：
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通讯作者：
M. Stampfer;S. Goldhaber;S. Yusuf;R. Peto;C. Hennekens
中科院分区：
文献类型：
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作者：
M. Stampfer;S. Goldhaber;S. Yusuf;R. Peto;C. Hennekens
急性心肌梗死患者冠状动脉内输注链激酶是缺血心肌再灌注的一种令人兴奋的创新技术，1 2 3 4，但其净效益尚未得到可靠的估计。链激酶静脉输注比冠状动脉内输注创伤小、费用低、容易，其作用已在随机试验中进行了研究。不可避免的是，当几个试验解决相同或相似的问题时，它们不太可能产生相同的结果，在这种情况下，对所有严格随机试验结果的概述可能是有用的。. .
Intracoronary infusion of streptokinase in patients with acute myocardial infarction is an exciting and innovative technique for reperfusion of the ischemic myocardium,1 2 3 4 but its net benefits have not yet been reliably estimated. Intravenous infusion of streptokinase is less invasive, less expensive, and easier than intracoronary infusion, and its effects have already been studied in randomized trials. Inevitably, when several trials address the same or a similar question, they are unlikely to yield identical results, and in these circumstances an overview of the results of all the strictly randomized trials can be useful.5 6 7 Although the play of chance may well produce . . .