Mechanisms and strategies of microbial cometabolism in the degradation of organic compounds - chlorinated ethylenes as the model.
Mechanisms and strategies of microbial cometabolism in the degradation of organic compounds - chlorinated ethylenes as the model.
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DOI：
10.2166/wst.2014.108
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发表时间：
2014-05
期刊：
影响因子：
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通讯作者：
W. Luo;Xiangcheng Zhu;Wenting Chen;Zhibing Duan;Lin Wang;Ya Zhou
中科院分区：
文献类型：
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作者：
W. Luo;Xiangcheng Zhu;Wenting Chen;Zhibing Duan;Lin Wang;Ya Zhou
普遍存在的微生物共代谢为我们提供了去除人造异生物质的有效途径。然而，由于微生物共代谢的研究和应用基础尚不明确，因此，对有毒有机物的共代谢生物修复尚未得到广泛的开展。本文综述了微生物彗星效应机理的研究进展，并对其应用前景进行了展望。讨论了共代谢生物修复中的关键酶、酶抑制、毒性效应和能量调控等关键因素。本文对氯代乙烯的微生物共代谢进行了综述，进一步证实了上述基本原理和假设，并认为氯代乙烯的微生物共代谢是利用微生物共代谢进行污染修复的典范。后续的前瞻性研究将有助于我们深入了解微生物彗星效应的模糊机制，并帮助我们开发更有效的渐进性污染生物修复技术。
The universal microbial cometabolism provides us with an effective approach to remove man-made xenobiotics. However, the cometabolic bioremediation of toxic organic compounds has not been widely initiated due to the obscure underlying fundamentals in the studies or applications of microbial cometabolism. This review summarizes the current research trends in mechanistic understanding of microbial cometabolism, especially with regard to its potential applications. The crucial factors including key enzyme, enzyme inhibition, toxic effects and energy regulation are discussed, which all significantly contribute to the cometabolic bioremediation of pollutants. The presented review of chlorinated ethylene cometabolism in this overview has further confirmed the fundamentals and hypotheses mentioned above, and thus cometabolism of chlorinated ethylenes has been regarded as a role model of pollution remediation technology using microbial cometabolism. The subsequent prospective research should provide insights into the ambiguous mechanism of microbial cometabolism and help us to develop more efficient bioremediation of progressive pollution.