Health-related quality-of-life in low-income, uninsured men with prostate cancer

Health-related quality-of-life in low-income, uninsured men with prostate cancer
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DOI:
10.1353/hpu.2005.0037
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发表时间:
2005-05-01
影响因子:
1.4
通讯作者:
Litwin, MS
Litwin, MS
中科院分区:
医学4区
文献类型:
--
作者:
Krupski, TL;Fink, A;Litwin, MS

文献摘要

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目的是描述低收入前列腺癌男性的健康相关生活质量 (HRQOL)。受试者来自全州公共援助前列腺癌计划。电话和邮件调查包括兰德公司 12 项健康调查和加州大学洛杉矶分校前列腺癌指数简表,并与文献中报告的一般人群中正常年龄匹配的未患癌症男性进行比较。在 286 名符合资格的男性中,233 名(81%)同意参加并完成了必要的项目。样本包括 51% 的西班牙裔、23% 的非西班牙裔白人和 17% 的非裔美国人。低收入男性在前列腺特异性和一般 HRQOL 的每个领域的得分均低于年龄匹配的一般人群对照。差异程度表明样本组和对照组之间在身体和情感功能的几乎每个领域都存在显着的临床差异。线性回归模型确定,在低收入男性中,西班牙裔种族和收入水平可以预测身体机能较差,而只有合并症可以预测心理健康。低收入前列腺癌患者的生活质量似乎比文献中报道的一般人群中年龄匹配的未患癌症男性要差得多。
The objective was to describe health-related quality-of-life (HRQOL) in low-income men with prostate cancer. Subjects were drawn from a statewide public assistance prostate cancer program. Telephone and mail surveys included the RAND 12-item Health Survey and UCLA Prostate Cancer Index Short Form and were compared with normative age-matched men without cancer from the general population reported on in the literature. Of 286 eligible men, 233 (81%) agreed to participate and completed the necessary items. The sample consisted of 51% Hispanics, 23% non-Hispanic whites, and 17% African Americans. The low-income men had worse scores in every domain of prostate-specific and general HRQOL than had the age-matched general population controls. The degree of disparity indicated substantial clinical differences in almost every domain of physical and emotional functioning between the sample group and the control group. Linear regression modeling determined that among the low-income men, Hispanic race, and income level were predictive of worse physical functioning, whereas only comorbidities predicted mental health. Low-income patients with prostate cancer appear to have quality-of-life profiles that are meaningfully worse than age-matched men from the general population without cancer reported on in the literature.