Atopic Dermatitis and Respiratory Allergy: What is the Link.
Atopic Dermatitis and Respiratory Allergy: What is the Link.
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DOI：
10.1007/s13671-015-0121-6
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发表时间：
2015
影响因子：
1.6
通讯作者：
Custovic A
中科院分区：
文献类型：
--
作者：
Belgrave DC;Simpson A;Buchan IE;Custovic A
了解特应性皮炎和呼吸道过敏的病因和进展可能会阐明旨在减轻哮喘和过敏性疾病全球负担的早期预防和管理策略。在本文中，我们回顾了目前关于特应性皮炎与儿童期和青春期早期呼吸道过敏随后进展之间联系的观点。机器学习和统计方法的进步促进了发现用于识别生物标志物的更精确的表型定义。了解特应性皮炎在呼吸道过敏发展中的作用可能最终使我们能够确定更有效的治疗策略，从而减少与这些疾病相关的患者和经济负担。
Understanding the aetiology and progression of atopic dermatitis and respiratory allergy may elucidate early preventative and management strategies aimed towards reducing the global burden of asthma and allergic disease. In this article, we review the current opinion concerning the link between atopic dermatitis and the subsequent progression of respiratory allergies during childhood and into early adolescence. Advances in machine learning and statistical methodology have facilitated the discovery of more refined definitions of phenotypes for identifying biomarkers. Understanding the role of atopic dermatitis in the development of respiratory allergy may ultimately allow us to determine more effective treatment strategies, thus reducing the patient and economic burden associated with these conditions.