Coming to our senses.
Coming to our senses.
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DOI：
10.1002/bies.20083
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发表时间：
2004-08
期刊：
影响因子：
--
通讯作者：
J. Treisman
中科院分区：
文献类型：
--
作者：
J. Treisman
感觉器官专门接收来自外部世界的不同类型的输入。然而，它们发展的共同特征表明，它们可能有一个共同的进化起源。在最近的一篇论文中，Niwa等人表明，果蝇的三个成年感觉器官都依赖于空间信号Decapentaplegic和Wingless来指定它们的位置，以及时间信号蜕皮激素来启动它们的发育。前神经基因无调是整合这些调控输入的重要位点。这些结果表明，存在一个原始的感觉器官的前体，这将根据其起源段的身份分化。作者认为，无眼基因控制着眼盘的身份，间接地从眼盘内的感觉器官前体产生了眼睛。
Sensory organs are specialized to receive different kinds of input from the outside world. However, common features of their development suggest that they could have a shared evolutionary origin. In a recent paper, Niwa et al. show that three Drosophila adult sensory organs all rely on the spatial signals Decapentaplegic and Wingless to specify their position, and the temporal signal ecdysone to initiate their development. The proneural gene atonal is an important site for integration of these regulatory inputs. These results suggest the existence of a primitive sensory organ precursor, which would differentiate according to the identity of its segment of origin. The authors argue that the eyeless gene controls eye disc identity, indirectly producing an eye from the sensory organ precursor within this disc.