Antioxidant activity of yeast mannans and their growth-promoting effect on Lactobacillus strains
Antioxidant activity of yeast mannans and their growth-promoting effect on Lactobacillus strains
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酵母甘露聚糖的抗氧化活性及其对乳酸菌的促生长作用
DOI：
10.1039/d1fo01470f
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发表时间：
2021
期刊：
影响因子：
6.1
通讯作者：
Guoqun Zhao
中科院分区：
文献类型：
--
作者：
Yong Wang;Chongyu Shen;Kai Huo;Di Cai;Guoqun Zhao
制备来自酿酒酵母的酵母甘露聚糖（123.2kDa、40.5kDa和21.3kDa）。随着酵母甘露聚糖分子量的降低，对Fe 2+、OH stec和O2 stec −的清除能力以及对脂质过氧化和DNA氧化损伤的保护能力增加。YM-90对Fe 2+、OH stec和O2 stec-的清除能力最强（25.32%，70.8%和61.5%），抗脂质过氧化能力达65.82%，远强于维生素C（VC），对硫代巴比妥酸反应性物质（TBARS）的抑制率达80.41%。而对DPPH自由基的清除率以YM-30最高（88.7%）。此外，酵母甘露聚糖对乳杆菌菌株的促生长作用得到进一步证实，YM-90使植物乳杆菌ZWR 5细胞活力提高了54.2%。结果表明，这种酵母甘露聚糖技术在治疗和营养品生产中具有潜在的工业应用前景。
Yeast mannans from Saccharomyces cerevisiae (123.2 kDa, 40.5 kDa and 21.3 kDa) were prepared. The scavenging abilities of Fe2+, OH˙, and O2˙− and protective capacities against lipid peroxidation and oxidative DNA damage increased with the reduction of the molecular weights of yeast mannans. The highest scavenging abilities of Fe2+, OH˙ and O2˙− (25.32%, 70.8%, and 61.5%) were observed with YM-90, and it showed an anti-lipid peroxidation capacity of 65.82%, which was much stronger than that of vitamin C (VC), with a thiobarbituric acid-reactive substance (TBARS) inhibition rate of 80.41%. However, the highest DPPH scavenging rate (88.7%) was exhibited by YM-30. In addition, the growth-promoting effect of yeast mannans on Lactobacillus strains was further confirmed, and a 54.2% increment of Lactobacillus plantarum ZWR5 cell viability was achieved by YM-90. The results indicated the potential industrial applications of this yeast mannan technology in therapeutic and nutraceutical production.