Copper and Zinc in the Serum, Urine, and Hair of Patients with Wilson's Disease Treated with Penicillamine and Zinc
Copper and Zinc in the Serum, Urine, and Hair of Patients with Wilson's Disease Treated with Penicillamine and Zinc
复制标题
DOI：
10.1007/s12011-009-8438-2
复制
发表时间：
2010-03-01
影响因子：
3.9
通讯作者：
Zdrazil, Libor
中科院分区：
文献类型：
--
作者：
Dastych, Milan;Prochazkova, Dagmar;Zdrazil, Libor
The purpose of this study was to determine the different levels of copper and zinc in the serum, urine, and scalp hair of patients with Wilson's disease receiving different, currently accepted methods of treatment to reduce the copper load (penicillamine-group 1, n=8; zinc-group 2, n=8; penicillamine+zinc-group 3, n=8). Blood, urine, and hair samples were collected from the patients. All three treatments resulted in a significant decrease of the serum copper levels. Significantly increased levels of zinc in the serum were detected in the patients in groups 2 and 3 (19.1 and 18.8 mu mol/l, respectively; p
