Cardiac abnormalities in chronic progressive external ophthalmoplegia.
Cardiac abnormalities in chronic progressive external ophthalmoplegia.
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慢性进行性眼外肌麻痹中的心脏异常。
DOI：
10.1136/hrt.38.5.526
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发表时间：
1976
影响因子：
--
通讯作者：
D. Jewitt
中科院分区：
文献类型：
--
作者：
M. McComish;A. Compston;D. Jewitt
本报告描述了一名 32 岁男性患有慢性进行性眼外肌麻痹 (CPEO) 综合征的心脏病。表面心电图显示一级房室传导阻滞和左束支传导阻滞，希氏束电图有HV延长。心内膜心肌活检在光镜下可见肥厚变化，在电镜下可见线粒体数量增多，但结构正常。植入永久按需起搏器是因为这些患者容易发生完全性心脏传导阻滞。
This report describes heart disease in a 32-year-old man with the syndrome of chronic progressive external ophthalmoplegia (CPEO). The surface electrocardiogram showed first degree AV block and left bundle-branch block and there was HV prolongation on the His bundle electrogram. Endomyocardial biopsy showed the changes of hypertrophy on light microscopy, and on electron microscopy there were increased numbers of mitochondria which appeared structurally normal. A permanent demand pacemaker was inserted because these patients are prone to develop complete heart block.