ULTRASOUND EXAMINATION OF SKIN THICKNESS IN PATIENTS WITH PROGRESSIVE SYSTEMIC-SCLEROSIS (SCLERODERMA)
ULTRASOUND EXAMINATION OF SKIN THICKNESS IN PATIENTS WITH PROGRESSIVE SYSTEMIC-SCLEROSIS (SCLERODERMA)
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DOI：
10.1177/028418518602700117
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发表时间：
1986-01-01
期刊：
影响因子：
--
通讯作者：
WOLLHEIM, F
中科院分区：
文献类型：
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作者：
AKESSON, A;FORSBERG, L;WOLLHEIM, F
对40例进行性系统性硬化症（硬皮病）患者和10名健康对照者进行了一种新的超声测量皮肤厚度的技术评估。采用高频（10 MHz）动态超声检查两指近、中指骨。对照受试者在两个不同场合的测量结果表明，该技术具有良好的再现性，标准偏差为0.06 mm。硬皮病患者皮肤较厚3.3。0.7 mm(平均±。SD)与对照组相比为2.5 .+-。0.2 mm （p < 0.001）。皮肤厚度与病程无关系。这种方法可以用来监测皮肤厚度随时间的变化。
A new ultrasound technique for measuring skin thickness in 40 patients with progressive systemic sclerosis (scleroderma) and in 10 healthy control subjects has been evaluated. High frequency (10 MHz) dynamic ultrasound examination was performed at the proximal and middle phalanges of both second fingers. Measurements of the control subjects on two separate occasions demonstrated a good reproducibility of the technique with a standard deviation of 0.06 mm. The skin was thicker in patients with scleroderma 3.3 .+-. 0.7 mm (mean .+-. SD) compared with control subjects 2.5 .+-. 0.2 mm (p < 0.001). No relation between skin thickness and duration of disease was observed. This method can be used to monitor changes in skin thickness over time.