First imaging demonstration of a crosshair light-sharing PET detector
First imaging demonstration of a crosshair light-sharing PET detector
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DOI：
10.1088/1361-6560/abe839
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发表时间：
2021-02
影响因子：
3.5
通讯作者：
E. Yoshida;G. Akamatsu;H. Tashima;K. Kamada;A. Yoshikawa;T. Yamaya
中科院分区：
文献类型：
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作者：
E. Yoshida;G. Akamatsu;H. Tashima;K. Kamada;A. Yoshikawa;T. Yamaya
十字准线光共享（CLS）PET探测器是我们最初的相互作用深度（DOI）探测器，它基于单端读出方案，具有与光电传感器大小相当的四等分晶体。在这项工作中，我们开发了32个CLS PET探测器，每个探测器由多像素光子计数器（MPPC）阵列和钆细铝石榴石（GFAG）晶体组成，我们开发了一个小型动物大小的PET的台式原型。每个GFAG晶体为1.45 × 1.45 × 15 mm 3。MPPC的表面积为3.0 × 3.0 mm2。台式原型有两个16个探测器块的探测器环。环直径和轴向视野分别为14.2 cm和4.9 cm。使用的数据采集系统是PETsys硅光电倍增管读出系统。通过将查找表应用于2D位置直方图，将连续的DOI信息分箱为三个DOI层。此外，使用DOI信息校正能量和定时信息。经标定后，能量分辨率和符合时间分辨率分别为14.6%和531ps。通过迭代重建方法获得的小棒体模的成像测试结果显示，在DOI信息的帮助下，1.6 mm棒清晰分离。
The crosshair light-sharing (CLS) PET detector is our original depth-of-interaction (DOI) detector, which is based on a single-ended readout scheme with quadrisected crystals comparable in size to a photo-sensor. In this work, we developed 32 CLS PET detectors, each of which consisted of a multi-pixel photon counter (MPPC) array and gadolinium fine aluminum garnet (GFAG) crystals, and we developed a benchtop prototype of a small animal size PET. Each GFAG crystal was 1.45 × 1.45 × 15 mm3. The MPPC had a surface area of 3.0 × 3.0 mm2. The benchtop prototype had two detector rings of 16 detector blocks. The ring diameter and axial field-of-view were 14.2 cm and 4.9 cm, respectively. The data acquisition system used was the PETsys silicon photomultiplier readout system. The continuous DOI information was binned into three DOI layers by applying a look-up-table to a 2D position histogram. Also, energy and timing information was corrected using DOI information. After the calibration procedure, the energy resolution and the coincidence time resolution were 14.6% and 531 ps, respectively. Imaging test results of a small rod phantom obtained by an iterative reconstruction method showed clear separation of 1.6 mm rods with the help of DOI information.