Relationship between Helicobacter pylori infection and Alzheimer disease

Relationship between Helicobacter pylori infection and Alzheimer disease
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DOI:
10.1212/01.wnl.0000203644.68059.5f
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发表时间:
2006-03-28
期刊:
影响因子:
9.9
通讯作者:
Venizelos, I
Venizelos, I
中科院分区:
医学1区
文献类型:
--
作者:
Kountouras, J;Tsolaki, M;Venizelos, I

文献摘要

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作者通过对Hp-I的组织学诊断,探讨了幽门螺杆菌感染(Hp-I)与阿尔茨海默病(AD)的关系。50例AD患者和30例无AD的缺铁性贫血对照者被纳入研究。阿尔茨海默病患者Hp-I的组织学患病率为88%,对照组为46.7% (p < 0.001)。
The authors investigated the association between Helicobacter pylori infection (Hp-I) and Alzheimer disease (AD) by using histology for diagnosis of Hp-I. Fifty patients with AD and 30 iron deficiency anemic control participants without AD were included. The histologic prevalence of Hp-I was 88% in patients with AD and 46.7% in controls (p < 0.001).