Keeping in touch with the visual system: spatial alignment and multisensory integration of visual-somatosensory inputs.
Keeping in touch with the visual system: spatial alignment and multisensory integration of visual-somatosensory inputs.
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DOI：
10.3389/fpsyg.2015.01068
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发表时间：
2015
影响因子：
3.8
通讯作者：
Foxe JJ
中科院分区：
文献类型：
--
作者：
Mahoney JR;Molholm S;Butler JS;Sehatpour P;Gomez-Ramirez M;Ritter W;Foxe JJ
相关的感觉输入沿着个体感觉加工层次到达皮层的多感觉会聚区，在那里输入以整合的方式进行加工。多感觉会聚区的确切层次及其输入时间仍在争论中，尽管越来越多的证据表明多感觉整合（MSI）在非常早期的感觉处理水平。虽然MSI被认为是由刺激属性，包括空间，时间和幅度，这些规则的违反已被记录。本研究的目的是确定，无论是心理和电生理，是否存在差异的视觉-体感（VS）整合模式的刺激呈现给相同的与相反的hemifields。使用高密度电映射和补充的心理物理数据，我们研究了多感官综合处理的视觉和体感输入的组合，提出了左，右空间位置。我们评估了如何早期在感觉处理VS的相互作用被认为是在事件相关电位和视觉和体感元素的空间对齐是否导致差异整合效应。所有VS配对的反应时间显着快于那些unisensory条件，无论空间对齐，指向在所有条件下的综合多感官处理的参与。在支持，电生理结果显示多感官同时VS和总结V + S反应之间的显着差异，无论空间对齐的组成输入。尽管如此，多感官效应在对齐条件下更早出现，并且在右侧输入的情况下（仅从55 ms开始）特别强大。与以前的工作对视听和听觉体感输入，目前的工作表明一定程度的空间特异性，最早可检测到的多感官综合效应VS配对。
Correlated sensory inputs coursing along the individual sensory processing hierarchies arrive at multisensory convergence zones in cortex where inputs are processed in an integrative manner. The exact hierarchical level of multisensory convergence zones and the timing of their inputs are still under debate, although increasingly, evidence points to multisensory integration (MSI) at very early sensory processing levels. While MSI is said to be governed by stimulus properties including space, time, and magnitude, violations of these rules have been documented. The objective of the current study was to determine, both psychophysically and electrophysiologically, whether differential visual-somatosensory (VS) integration patterns exist for stimuli presented to the same versus opposite hemifields. Using high-density electrical mapping and complementary psychophysical data, we examined multisensory integrative processing for combinations of visual and somatosensory inputs presented to both left and right spatial locations. We assessed how early during sensory processing VS interactions were seen in the event-related potential and whether spatial alignment of the visual and somatosensory elements resulted in differential integration effects. Reaction times to all VS pairings were significantly faster than those to the unisensory conditions, regardless of spatial alignment, pointing to engagement of integrative multisensory processing in all conditions. In support, electrophysiological results revealed significant differences between multisensory simultaneous VS and summed V + S responses, regardless of the spatial alignment of the constituent inputs. Nonetheless, multisensory effects were earlier in the aligned conditions, and were found to be particularly robust in the case of right-sided inputs (beginning at just 55 ms). In contrast to previous work on audio-visual and audio-somatosensory inputs, the current work suggests a degree of spatial specificity to the earliest detectable multisensory integrative effects in response to VS pairings.