Intestinal stricture in Crohn's disease.
Intestinal stricture in Crohn's disease.
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DOI：
10.5217/ir.2015.13.1.19
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发表时间：
2015-01
影响因子：
4.9
通讯作者：
Wei SC
中科院分区：
文献类型：
--
作者：
Chang CW;Wong JM;Tung CC;Shih IL;Wang HY;Wei SC
克罗恩病（CD）是一种病因不明的慢性炎症疾病，累及胃肠道的任何部分。近年来，CD的发病率和患病率在亚洲呈上升趋势。一半的CD患者在诊断后20年内会出现肠道并发症，如狭窄或瘘管。25%的CD患者至少有一次小肠狭窄，10%的患者至少有一次结肠狭窄，并导致严重的并发症。大多数患者在其一生中至少需要一次手术。早期诊断、早期评估、及时处理是预防此类患者致残和死亡的重要措施。本文就CD狭窄的发生率、狭窄的病因、诊断和处理方法作一综述。
Crohn's disease (CD) is a disease with chronic inflammation of unknown etiology involving any part of the gastrointestinal tract. The incidence and prevalence of CD are increasing recently in Asia. Half of the CD patients will have intestinal complications, such as strictures or fistulas, within 20 years after diagnosis. Twenty-five percentage of CD patients have had at least one small bowel stricture and 10% have had at least one colonic stricture and lead to significant complications. Most of these patients will require at least one surgery during their lifetime. Early diagnosis and evaluation with adequate managements for the patients can prevent disability and mortality of these patient. Here, we reviewed the current incidence of CD with stricture, the etiology of stricture, and how to diagnose and manage the stricture.