Sex, clinical presentation, and outcome in patients with acute coronary syndromes
Sex, clinical presentation, and outcome in patients with acute coronary syndromes
复制标题
DOI：
10.1056/nejm199907223410402
复制
发表时间：
1999-07-22
影响因子：
158.5
通讯作者：
Califf, RM
中科院分区：
文献类型：
--
作者：
Hochman, JS;Tamis, JE;Califf, RM
背景研究表明，患有急性心肌梗死的女性患者的院内和长期结果比男性差。 方法 为了评估基于性别的表现和结果差异，我们检查了急性冠状动脉综合征 IIb 中开放闭塞冠状动脉策略的全球使用研究的数据，该研究纳入了 12,142 名急性冠状动脉患者（3662 名女性和 8480 名男性） 综合征，包括 ST 段抬高的梗塞、非 ST 段抬高的梗塞和不稳定型心绞痛。 结果 总体而言，女性比男性年龄更大，并且患有糖尿病、高血压和既往充血性心力衰竭的比率显着更高。他们既往心肌梗塞的发生率明显较低，而且吸烟的可能性也较小。患有 ST 段抬高梗塞的女性比例低于男性（27.2% vs. 37.0%，P
Background Studies have reported that women with acute myocardial infarction have in-hospital and long-term outcomes that are worse than those of men.Methods To assess sex-based differences in presentation and outcome, we examined data from the Global Use of Strategies to Open Occluded Coronary Arteries in Acute Coronary Syndromes IIb study, which enrolled 12,142 patients (3662 women and 8480 men) with acute coronary syndromes, including infarction with ST-segment elevation, infarction with no ST-segment elevation, and unstable angina.Results Overall, the women were older than the men and had significantly higher rates of diabetes, hypertension, and prior congestive heart failure. They had significantly lower rates of prior myocardial infarction and were less likely ever to have smoked. A smaller percentage of women than men had infarction with ST elevation (27.2 percent vs. 37.0 percent, P