Gray matter abnormalities in Internet addiction: A voxel-based morphometry study
Gray matter abnormalities in Internet addiction: A voxel-based morphometry study
复制标题
DOI：
10.1016/j.ejrad.2009.10.025
复制
发表时间：
2011-07-01
影响因子：
3.3
通讯作者：
Lei, Hao
中科院分区：
文献类型：
--
作者：
Zhou, Yan;Lin, Fu-chun;Lei, Hao
背景资料：本研究采用基于体素的形态计量学（voxel-based morphometry，VBM）技术，对18例网络成瘾青少年和15名年龄、性别匹配的健康对照者进行了高分辨率T1加权结构磁共振成像（MRI）研究，探讨网络成瘾青少年脑灰质密度（graymatter density，GMD）的变化。对两组进行高分辨率T1加权磁共振成像扫描。结果：与健康对照组相比，IA青少年的左前扣带回、左后扣带回、左舌回和左舌回的GMD明显降低。结论：IA青少年存在脑结构的改变，这一发现可能为IA的发病机制提供了新的认识。(C)2009爱思唯尔爱尔兰有限公司保留所有权利。
Background: This study aims to investigate brain gray matter density (GMD) changes in adolescents with Internet addiction (IA) using voxel-based morphometry (VBM) analysis on high-resolution T1-weighted structural magnetic resonance images.Methods: Eighteen IA adolescents and 15 age- and gender-matched healthy controls took part in this study. High-resolution T1-weighted magnetic resonance imaging scans were performed on the two groups. VBM analysis was used to compare the GMD between the two groups.Results: Compared with healthy controls, IA adolescents had lower GMD in the left anterior cingulate cortex, left posterior cingulate cortex, left insula, and left lingual gyrus.Conclusions: Our findings suggested that brain structural changes were present in IA adolescents, and this finding may provide a new insight into the pathogenesis of IA. (C) 2009 Elsevier Ireland Ltd. All rights reserved.