SPORADIC NON-A, NON-B HEPATITIS - FREQUENCY AND EPIDEMIOLOGY IN AN URBAN UNITED-STATES POPULATION
SPORADIC NON-A, NON-B HEPATITIS - FREQUENCY AND EPIDEMIOLOGY IN AN URBAN UNITED-STATES POPULATION
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DOI：
10.1093/infdis/145.6.886
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发表时间：
1982-01-01
影响因子：
6.4
通讯作者：
MATANOSKI, GM
中科院分区：
文献类型：
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作者：
ALTER, MJ;GERETY, RJ;MATANOSKI, GM
1979年2月至1980年8月，马里兰州巴尔的摩的五家医院发现了急性病毒性肝炎患者。在血清学诊断为肝炎的295名患者中，42%患有非甲非乙型肝炎，48%患有乙型肝炎，10%患有甲型肝炎。与没有肝病的匹配对照组患者相比，非甲非乙型肝炎患者更多地接受过输血(11%对0，P<；0.001)，使用过肠外药物(42%对4%，P<；0.001)，被聘用为直接患者护理或医院实验室工作的卫生工作者(6%对3%，P<；0.001)。与其他肝炎患者有过私人接触(16%对1%，P<；0.001)，或进食过生贝类(34%对20%，P<；0.01)。非甲非乙型肝炎患者既往有肝炎病史和血清学标志物提示有乙肝感染史的比例高于对照组。在80例非甲非乙型肝炎患者中，34例(42.5%)为慢性非甲非乙型肝炎。
Patients with acute viral hepatitis were identified at five hospitals in Baltimore, Maryland between February 1979-August 1980. Of the 295 patients with serologically diagnosed hepatitis, 42% had non-A, non-B hepatitis; 48% had hepatitis B; and 10% had hepatitis A. Compared with matched control patients with no liver disease, patients with non-A, non-B hepatitis more often had received a blood transfusion (11% vs. 0,P< 0.001), used parenteral drugs (42% vs. 4%,P< 0.001), were employed as health workers in direct patient care or hospital laboratory work (6% vs. 3%,P< 0.05), had personal contact with others who had hepatitis (16% vs. 1%,P< 0.001), or had ingested raw shellfish (34% vs. 20%,P< 0.01). A history of previous clinical hepatitis and serologic markers indicating previous hepatitis B infection were found in patients with non-A, non-B hepatitis more often than in the control patients. Chronic non-A, non-B hepatitis was found in 34 (42.5%) of 80 patients with non-A, non-B hepatitis.