Intraspinal primitive neuroectodermal tumor: Imaging findings in six cases
Intraspinal primitive neuroectodermal tumor: Imaging findings in six cases
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DOI：
10.1016/j.ejrad.2010.06.005
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发表时间：
2011-11-01
影响因子：
3.3
通讯作者：
Shen, Jun
中科院分区：
文献类型：
--
作者：
Duan, Xiao-Hui;Ban, Xiao-Hua;Shen, Jun
目的：回顾性分析6例经手术病理证实的椎管内原始神经外胚层肿瘤的CT和MRI表现，探讨其影像学特征。结果：6例患者中，4例为硬膜外病变，2例为硬膜内、髓外病变。病灶边界清楚，T1WI呈不均匀等或低信号，T2WI呈高信号，CT呈中等密度影，增强后呈不均匀强化。4例患者的病变延伸穿过椎间孔并形成一个巨大的椎旁软组织肿块，4例患者的椎体骨受累。虽然影像学表现对椎管内原始神经外胚层肿瘤没有特异性，但当MRI显示硬膜内，髓外或硬膜外大的界限清楚的肿块，从椎间孔延伸出来，侵犯椎旁软组织或椎骨，见于年轻患者。(C)2010爱思唯尔爱尔兰有限公司版权所有。
Purpose: To retrospectively review CT and MRI findings in a series of six intraspinal primitive neuroectoderal tumors and to find out their radiological features.Methods: CT and MRI of six patients with surgically and pathologically proved intraspinal primitive neuroectoderal tumor were retrospectively reviewed. The tumor location, morphological features, signal intensity, calcification, contrast enhancement characteristics, involvement of paraspinal soft tissues and adjacent bony structures were assessed.Results: Of six patients, four had extradural lesions and two had intradural, extramedullary lesions. Most lesions were well defined and manifested heterogeneous iso- or hypo-intense signal on T1-weighted imaging and hyper-intense signal on T2-weighted imaging and moderate attenuation on CT, and were heterogeneously enhanced after contrast enhancement. The lesion extending through the intervertebral foramen with a large paraspinal soft tissue mass formed was found in four patients and vertebral bone involvement was seen in four patients.Conclusions: Although imaging findings are not specific of intraspinal primitive neuroectoderal tumor, this diagnosis could be suggested when MR imaging depicts an intradural, extramedullary or extradural large well-circumscribed mass which extends out from intervertebral foramen and invades paraspinal soft tissues or vertebral bones in a young patient. (C) 2010 Elsevier Ireland Ltd. All rights reserved.