HEMODYNAMIC ASPECTS OF CEREBRAL ARTERIOVENOUS-MALFORMATIONS

HEMODYNAMIC ASPECTS OF CEREBRAL ARTERIOVENOUS-MALFORMATIONS
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DOI:
10.3171/jns.1980.53.4.0456
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发表时间:
1980-01-01
影响因子:
4.1
通讯作者:
GRIP, A
GRIP, A
中科院分区:
医学1区
文献类型:
--
作者:
NORNES, H;GRIP, A

文献摘要

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对16例脑动静脉畸形(AVM)全切术患者的局部血流动力学进行了研究。应用定向多普勒技术记录AVM供血和引流血管的血流速度。单支供血动脉的计算流量范围为3-550 ml/min(平均180 ml/min)。9例患者的总AVM流量估计值为150至> 900 ml/min(平均490 ml/min)。在AVM入口处对供血动脉进行压力记录。在所有病例中,该压力远低于全身动脉血压,范围为40-77 mm Hg(平均56 mm Hg)。在暂时咬合时,该残端压力立即从55-95 mm Hg(平均76 mm Hg)升高。闭塞前引流静脉压范围为8-23 mm Hg(平均15 mm Hg),闭塞后降至0。这些数据和其他临床观察讨论相邻的脑组织灌注,特别强调的循环突破,可以遵循这些高容量分流闭塞。
Local hemodynamics were studied in 16 patients undergoing total extirpation of cerebral arteriovenous malformation (AVM). Directional Doppler technique was used for the registration of blood velocities in vessels feeding and draining the AVM. Calculated flow in single feeding arteries ranged from 3-550 ml/min (average, 180 ml/min). An estimation of total AVM flow was possible in 9 patients and ranged from 150 to > 900 ml/min (average, 490 ml/min). Pressure recordings were made from feeding arteries at their entrance to the AVM. This pressure was well below the systemic arterial blood pressure in all cases and ranged from 40-77 mm Hg (average, 56 mm Hg). On temporary occlusion, this stump pressure instantly rose from 55-95 mm Hg (average, 76 mm Hg). Draining vein pressure before occlusion ranged from 8-23 mm Hg (average, 15 mm Hg) and fell to 0 when the AVM was occluded. This data and other clinical observations are discussed with regard to adjacent brain-tissue perfusion, with special emphasis on the circulatory breakthrough that can follow the occlusion of these high-capacity shunts.