Novel 3D magnetic tweezer system for microswimmer manipulations
Novel 3D magnetic tweezer system for microswimmer manipulations
复制标题
用于微型游泳器操作的新型 3D 磁力镊子系统
DOI：
10.1109/urai.2017.7992758
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发表时间：
2017
期刊：
影响因子：
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通讯作者：
M. J. Kim
中科院分区：
文献类型：
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作者：
Xiao Zhang;Hoyeon Kim;L. Rogowski;Samuel Sheckman;M. J. Kim
微型机器人在医学领域有着巨大的应用潜力，如对人体的微创、药物输送和药物成像等。磁镊作为一种强有力的微操作工具，受到了广泛的关注。然而，以往的研究主要是利用磁镊在很小的工作空间与二维控制输入。设计并实现了一种具有宽工作范围的三维磁镊系统，利用磁场梯度产生的磁力操纵不同数量微珠组装的微泳者。使用我们设计的磁性镊子进行的实验演示了操纵的microswimmer，以遵循所需的轨迹，速度控制和群体运动。我们证明，建议的磁镊子有足够的权力和可控性，以操纵微游泳者在牛顿流体环境。虽然目前软件级控制方法的发展有限，但采用手动控制方法可以实现灵活且相对精确的运动行为。
Microrobots have an enormous potential in medical applications such as the minimal invasion to human body, drug delivery and drug imaging. Magnetic tweezers, as a very powerful tool in micro manipulation, has been investigated by many researchers. However, most of the previous researches mainly have utilized the magnetic tweezer on very small working space with two-dimensional control inputs. This paper discusses the design and implementation of a 3D magnetic tweezer system with a wide working range to manipulate microswimmers, which are assembled with different amount of microbeads, by utilizing magnetic forces created from magnetic field gradient. Experiments performed using our designed magnetic tweezer demonstrate the manipulating of microswimmers in order to follow the desired trajectories, speed control and swarm motion. We prove that the suggested magnetic tweezer has enough power and the controllability to manipulate microswimmers in Newtonian fluid environments. Even though we had the limited development of software level control method at present state, it is available to perform agile and relatively accurate moving behaviors using manual control method.
磁扭转细胞术。
影响因子：
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作者：
Kasza,KarenE;Vader,David;Köster,Sarah;Wang,Ning;Weitz,DavidA
通讯作者：
Weitz,DavidA