Changing trends in incidence of lung cancer by histologic type in Scotland
Changing trends in incidence of lung cancer by histologic type in Scotland
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DOI：
10.1002/ijc.10661
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发表时间：
2002-11-10
影响因子：
6.4
通讯作者：
MacFarlane, GJ
中科院分区：
文献类型：
--
作者：
Harkness, EF;Brewster, DH;MacFarlane, GJ
肺癌是全世界主要的公共卫生问题。我们的研究旨在调查 1959-97 年苏格兰肺癌发病率趋势以及 1975-97 年按组织学类型划分的趋势。在苏格兰，肺癌是男性中最常见的癌症，也是女性中第二常见的癌症。由于存活率较低，发病率和死亡率的趋势呈现相似的模式。在美国和欧洲许多地区，鳞状细胞癌的发病率有所下降，而腺癌的发病率却有所上升。数据取自苏格兰癌症登记处。通过将发病率标准化为世界标准人口来检查发病率趋势。按诊断年份和出生年中检查年龄特定率。在苏格兰，自 20 世纪 70 年代末以来，男性肺癌发病率有所下降，而女性肺癌发病率则持续上升。腺癌的发病率随着时间的推移而增加，但鳞状细胞癌仍然是苏格兰肺癌的主要类型。尽管很大一部分肺癌（>20%）没有经过显微镜验证，但肺癌登记数据的质量随着时间的推移而不断提高。组织学类型的变化不太可能仅仅归因于诊断的进步。随着时间的推移，腺癌的发病率稳步上升，这可能是由于 20 世纪 50 年代香烟设计的变化所致。 (C) 2002 Wiley-Liss, Inc.
Lung cancer is a major public health concern worldwide. Our study aims to examine trends in incidence of lung cancer in Scotland during 1959-97 and by histologic type for 1975-97. In Scotland, lung cancer is the most commonly diagnosed cancer in men and is the second most commonly diagnosed cancer in women. Due to poor survival rates, trends in incidence and mortality display similar patterns. Within the United States and many parts of Europe, falls in the incidence of squamous cell carcinoma have occurred whilst the incidence of adenocarcinoma has increased. Data were extracted from the Scottish Cancer Registry. Trends in incidence were examined by standardising rates to the World Standard Population. Age-specific rates were examined by year of diagnosis and mid year of birth. In Scotland the incidence of lung cancer in men has fallen since the late 1970s, whereas incidence in women has continued to increase. Incidence rates of adenocarcinoma have increased over time but squamous cell carcinoma remains the predominant type of lung cancer in Scotland. The quality of lung cancer registration data has improved over time, although a large proportion of lung cancers (>20%) are not microscopically verified. Changes in histologic types are unlikely to be solely due to diagnostic advances. Rates of adenocarcinoma have increased steadily over time, and this may be due to changes in cigarette design during the 1950s. (C) 2002 Wiley-Liss, Inc.