FlyBase: enhancing Drosophila Gene Ontology annotations.
FlyBase: enhancing Drosophila Gene Ontology annotations.
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DOI：
10.1093/nar/gkn788
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发表时间：
2009-01
影响因子：
14.9
通讯作者：
FlyBase Consortium
中科院分区：
文献类型：
--
作者：
Tweedie S;Ashburner M;Falls K;Leyland P;McQuilton P;Marygold S;Millburn G;Osumi-Sutherland D;Schroeder A;Seal R;Zhang H;FlyBase Consortium
FlyBase（http://flybase.org）是一个有关果蝇遗传和基因组信息的数据库。基因本体论（GO）术语用于描述野生型基因产物的三个属性：它们的分子功能、它们所参与的生物学过程以及它们的亚细胞定位。本文描述了FlyBase基因本体论注释策略的近期变化，这些变化提高了基因本体论注释数据的质量。其中许多变化源于我们参与了基因本体论参考基因组注释项目——这是一个多数据库合作项目，为12个不同的物种生成全面的基因本体论注释集。
FlyBase (http://flybase.org) is a database of Drosophila genetic and genomic information. Gene Ontology (GO) terms are used to describe three attributes of wild-type gene products: their molecular function, the biological processes in which they play a role, and their subcellular location. This article describes recent changes to the FlyBase GO annotation strategy that are improving the quality of the GO annotation data. Many of these changes stem from our participation in the GO Reference Genome Annotation Project—a multi-database collaboration producing comprehensive GO annotation sets for 12 diverse species.