Serum 25-hydroxyvitamin D levels in vitamin D-insufficient hip fracture patients after supplementation with ergocalciferol and cholecalciferol
Serum 25-hydroxyvitamin D levels in vitamin D-insufficient hip fracture patients after supplementation with ergocalciferol and cholecalciferol
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DOI：
10.1016/j.bone.2009.07.015
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发表时间：
2009-11-01
期刊：
影响因子：
4.1
通讯作者：
Fraser, William D.
中科院分区：
文献类型：
--
作者：
Glendenning, Paul;Chew, Gerard T.;Fraser, William D.
维生素D缺乏通常与髋部骨折有关。然而，麦角钙化醇和胆钙化醇补充剂在该患者组中的等效性尚未在使用高效液相色谱法（HPLC）测量血清25-羟基维生素D（25 OHD）的随机试验中进行研究。本研究的目的是确定麦角钙化醇和胆钙化醇是否是治疗维生素D不足的髋部骨折患者的等效疗法。
Vitamin D insufficiency is commonly associated with hip fracture. However, the equipotency of ergocalciferol and cholecalciferol supplementation in this patient group has not been studied in a randomized trial using high-performance liquid chromatography (HPLC) measurement of serum 25-hydroxyvitamin D (25OHD). The objective of this study was to determine if ergocalciferol and cholecalciferol are equipotent therapies in vitamin D-insufficient hip fracture patients.Ninety five hip fracture inpatients with vitamin D insufficiency (250HD