Studies on Mammalian Fetuses in vitro During the Period of Organogenesis
Studies on Mammalian Fetuses in vitro During the Period of Organogenesis
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哺乳动物体外胎儿器官发生期的研究
DOI：
10.1007/978-1-4899-7212-5_2
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发表时间：
1973
期刊：
影响因子：
--
通讯作者：
D. New
中科院分区：
文献类型：
--
作者：
D. New
哺乳动物胎产的长期进化导致了母亲和胎儿之间如此紧密的结合，以至于在许多方面，胎儿可以被视为母亲暂时获得的额外器官。这个类比不应该做得太过分。与大多数器官不同的是，胎儿获得了这种联系的大部分好处，而且支付的费用很少，至少在生理货币上是如此。然而，在将胎儿从母体环境中移出并试图将其保持在体外时，我们立即遇到了许多培养移植器官的问题，首先应该考虑器官培养方法的适用性。近年来，不同类型的器官和组织培养的方法和结果已经在几本优秀的书籍中得到了充分的描述(例如Paul，1970；Willmer，1965)，这里甚至不试图对它们进行总结。但有几点可以注意到，这与器官发生期间的胎儿培养特别相关。
The long evolution of mammalian viviparity has resulted in such a close integration between mother and fetus that the fetus can in many ways be regarded as an extra organ temporarily acquired by the mother. The analogy should not be pressed too far. Unlike most organs, the fetus receives most of the benefits of the association and pays very little, at least in physiological currency, for its keep. Nevertheless, in removing the fetus from the maternal environment and attempting to maintain it in vitro, we immediately encounter many of the problems of culturing explanted organs, and should first consider how far organ culture methods are applicable. The methods and results of different types of organ and tissue culture have been fully described in several excellent books in recent years (e. g. Paul, 1970; Willmer, 1965), and no attempt will be made here even to summarize them. But a few points can be noted of particular relevance to the culture of fetuses during the period of organogenesis.