PHARMACOLOGIC EFFECTS IN MAN OF A SPECIFIC SEROTONIN-REUPTAKE INHIBITOR
PHARMACOLOGIC EFFECTS IN MAN OF A SPECIFIC SEROTONIN-REUPTAKE INHIBITOR
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DOI：
10.1126/science.619465
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发表时间：
1978-01-01
期刊：
影响因子：
56.9
通讯作者：
WONG, DT
中科院分区：
文献类型：
--
作者：
LEMBERGER, L;ROWE, H;WONG, DT
氟西汀（Lilly 110140）对正常志愿者血小板摄取[3 H] 5-羟色胺的抑制率为63%，该志愿者每天服用该药7天。该剂量对注射去甲肾上腺素或酪胺产生的升压反应没有影响。
Fluoxetine (Lilly 110140) caused a 63% inhibition of [3H]serotonin uptake into platelets obtained from normal volunteers to whom the drug was administered daily for 7 days. This dose had no effect on the usual pressor response produced by injections of norepinephrine or tyramine.