Recessed oxygen electrodes: getting more than PO2.
Recessed oxygen electrodes: getting more than PO2.
复制标题
嵌入式氧电极：获取超过 PO2。
DOI：
10.1007/978-1-4615-0205-0_29
复制
发表时间：
2003
影响因子：
--
通讯作者：
Buerk,DonaldG
中科院分区：
文献类型：
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作者：
Buerk,DonaldG
用凹进的金阴极(惠伦/奈尔型)02微电极研究O2在组织中的传输，已经发展了几种不同的实验技术。在60多年前相对较大的02阴极首次用于组织后，很快就认识到了严重的测量误差，包括组织02的电化学耗尽、对血流或对流混合(搅拌伪影)的敏感性、由于尖端大小而导致的信号平均以及在穿透过程中对细胞或微循环的破坏。为了解决这些问题，02个电极被小型化，尽管这并不总是消除PO2测量误差。
Several different experimental techniques have been developed using recessed gold cathode (Whalen/Nair-type) 02microelectrodes to investigate 02transport to tissue. After relatively large 02cathodes were first used in tissue over 60 years ago, serious measurement errors were soon recognized, including electrochemical depletion of tissue 02, sensitivity to blood flow or convective mixing (stirring artifact), signal averaging due to the tip size, and damage to cells or the microcirculation during penetration. To address these problems, 02electrodes were miniaturized, although this did not always eliminate PO2measurement errors.