Influence of Percutaneous Occlusion of Atrial Septal Defect on Left Atrial Function Evaluated Using 2D Speckle Tracking Echocardiography
Influence of Percutaneous Occlusion of Atrial Septal Defect on Left Atrial Function Evaluated Using 2D Speckle Tracking Echocardiography
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DOI：
10.1536/ihj.19-173
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发表时间：
2020-01-01
影响因子：
1.5
通讯作者：
Saitoh, Shinji
中科院分区：
文献类型：
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作者：
Suzuki, Kazutaka;Kato, Taichi;Saitoh, Shinji
经皮封堵房间隔缺损(ASD)已成为一种标准的治疗策略，但对此后的左房(LA)功能知之甚少。本研究利用二维超声心动图斑点追踪技术(2DE-ST)测量43例ASD患儿和13例正常对照儿童的左房应变，以确定其左房功能。在这些儿童中，12名接受了手术(ASD-S)，31名接受了封堵器(ASD-D)，13名作为对照。ASD后LA应变显著降低，ASD-S后LA应变无明显变化。提示经皮闭塞房间隔缺损可能会降低左房功能。此外，房间隔缺损装置的大小与左房应变呈负相关。这些结果提示ASD封堵器对LA功能有负面影响，可能对ASD的治疗策略的制定有重要意义。2DE-ST测量的左房应变可作为评价儿童房间隔缺损治疗后左房功能的良好指标。
Percutaneous occlusion of atrial septal defect (ASD) has recently become a standard therapeutic strategy, but little is known about left atrial (LA) function thereafter. The present study aimed to determine LA function in 43 children with ASD and 13 controls based on LA strain measured by two-dimensional echocardiographic speckle tracking (2DE-ST). Among these children, 12 underwent surgery (ASD-S), 31 had device closure (ASD-D), and 13 were included as controls. LA strain was significantly decreased after ASD-D but was not significantly altered after ASD-S. indicating that percutaneous occlusion of an ASD might decrease LA function. Furthermore, the size of the ASD device negatively correlated with LA strain. These results imply that ASD occlusion devices negatively influence LA function and might be important when decided therapeutic strategies for ASD. LA strain measured by 2DE-ST should become a good indicator of LA function after ASD treatment in children.